HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management
Abstract Human papillomavirus (HPV)-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …
The key differences between human papillomavirus-positive and-negative head and neck cancers: biological and clinical implications
SF Powell, L Vu, WC Spanos, D Pyeon - Cancers, 2021 - mdpi.com
Simple Summary Head and neck cancer (HNC) is the sixth most common cancer, causing
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …
HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources
A Lebeau, D Bruyere, P Roncarati, P Peixoto… - Nature …, 2022 - nature.com
Despite the high prevalence of both cervico-vaginal human papillomavirus (HPV) infection
and bacterial vaginosis (BV) worldwide, their causal relationship remains unclear. While BV …
and bacterial vaginosis (BV) worldwide, their causal relationship remains unclear. While BV …
[HTML][HTML] HPV E7 inhibits cell pyroptosis by promoting TRIM21-mediated degradation and ubiquitination of the IFI16 inflammasome
Y Song, X Wu, Y Xu, J Zhu, J Li, Z Zou… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Human papillomavirus (HPV) is a DNA virus that causes sexually transmitted infections. The
HPV oncoprotein E7 plays a critical role in the regulation of host immunity to promote the …
HPV oncoprotein E7 plays a critical role in the regulation of host immunity to promote the …
Immunology of HPV-mediated cervical cancer: current understanding
Human papilloma virus (HPV) has emerged as a primary cause of cervical cancer
worldwide. HPV is a relatively small (55 nm in diameter) and non-enveloped virus …
worldwide. HPV is a relatively small (55 nm in diameter) and non-enveloped virus …
Activities of stromal and immune cells in HPV-related cancers
MR Barros, CML de Melo, MLCMGR Barros… - Journal of Experimental …, 2018 - Springer
The immune system is composed of immune as well as non-immune cells. As this system is
a well-established component of human papillomavirus-(HPV)-related carcinogenesis, high …
a well-established component of human papillomavirus-(HPV)-related carcinogenesis, high …
DNA tumor virus regulation of host DNA methylation and its implications for immune evasion and oncogenesis
SK Kuss-Duerkop, JA Westrich, D Pyeon - Viruses, 2018 - mdpi.com
Viruses have evolved various mechanisms to evade host immunity and ensure efficient viral
replication and persistence. Several DNA tumor viruses modulate host DNA …
replication and persistence. Several DNA tumor viruses modulate host DNA …
CXCL14 suppresses human papillomavirus-associated head and neck cancer through antigen-specific CD8+ T-cell responses by upregulating MHC-I expression
JA Westrich, DW Vermeer, A Silva, S Bonney… - Oncogene, 2019 - nature.com
Evasion of the host immune responses is critical for both persistent human papillomavirus
(HPV) infection and associated cancer progression. We have previously shown that …
(HPV) infection and associated cancer progression. We have previously shown that …
Virus hijacking of host epigenetic machinery to impair immune response
M Locatelli, S Faure-Dupuy - Journal of Virology, 2023 - Am Soc Microbiol
Epigenetic modifications, such as DNA hypermethylation, histone acetylation/methylation, or
nucleosome positioning, result in differential gene expression. These modifications can …
nucleosome positioning, result in differential gene expression. These modifications can …
The promise of combining cancer vaccine and checkpoint blockade for treating HPV-related cancer
T Shibata, BJ Lieblong, T Sasagawa… - Cancer treatment …, 2019 - Elsevier
Human papillomavirus (HPV)-associated intraepithelial neoplasia or cancers are ideal
candidates for cancer immunotherapy since HPV oncoproteins, such as E6 and E7 proteins …
candidates for cancer immunotherapy since HPV oncoproteins, such as E6 and E7 proteins …