Recent advances in Brucella abortus vaccines

EMS Dorneles, N Sriranganathan, AP Lage - Veterinary research, 2015 - Springer
Brucella abortus vaccines play a central role in bovine brucellosis control/eradication
programs and have been successfully used worldwide for decades. Strain 19 and RB51 are …

Evaluation of brucellosis vaccines: a comprehensive review

M Heidary, S Dashtbin, R Ghanavati… - Frontiers in Veterinary …, 2022 - frontiersin.org
Brucellosis is a bacterial zoonosis caused by Brucella spp. which can lead to heavy
economic losses and severe human diseases. Thus, controlling brucellosis is very …

Development of a multi-epitope peptide vaccine inducing robust T cell responses against brucellosis using immunoinformatics based approaches

M Saadi, A Karkhah, HR Nouri - Infection, Genetics and Evolution, 2017 - Elsevier
Current investigations have demonstrated that a multi-epitope peptide vaccine targeting
multiple antigens could be considered as an ideal approach for prevention and treatment of …

A History of the Development of Brucella Vaccines

ED Avila-Calderón, A Lopez-Merino… - BioMed research …, 2013 - Wiley Online Library
Brucellosis is a worldwide zoonosis affecting animal and human health. In the last several
decades, much research has been performed to develop safer Brucella vaccines to control …

Towards a Brucella vaccine for humans

SD Perkins, SJ Smither, HS Atkins - FEMS microbiology reviews, 2010 - academic.oup.com
There is currently no licensed vaccine for brucellosis in humans. Available animal vaccines
may cause disease and are considered unsuitable for use in humans. However, the …

Development and trial of vaccines against Brucella

J Lalsiamthara, JH Lee - Journal of Veterinary Science, 2017 - synapse.koreamed.org
The search for ideal brucellosis vaccines remains active today. Currently, no licensed
human or canine anti-brucellosis vaccines are available. In bovines, the most successful …

The advances in brucellosis vaccines

H Hou, X Liu, Q Peng - Vaccine, 2019 - Elsevier
Brucellosis is a worldwide zoonosis affecting animal and human health. Till now, there is no
effective vaccine licensed for brucellosis in humans. Although M5, H38 and 45/20 vaccines …

Progress in Brucella vaccine development

X Yang, JA Skyberg, L Cao, B Clapp, T Thornburg… - Frontiers in biology, 2013 - Springer
Brucella spp. are zoonotic, facultative intracellular pathogens, which cause animal and
human disease. Animal disease results in abortion of fetuses; in humans, it manifests flu-like …

Immunization with Recombinant Brucella Species Outer Membrane Protein Omp16 or Omp19 in Adjuvant Induces Specific CD4+ and CD8+ T Cells as Well as Systemic and …

KA Pasquevich, SM Estein, CG Samartino… - Infection and …, 2009 - Am Soc Microbiol
Available vaccines against Brucella spp. are live attenuated Brucella strains. In order to
engineer a better vaccine to be used in animals and humans, our laboratory aims to develop …

Brucellosis vaccines for livestock

ZI Goodwin, DW Pascual - Veterinary immunology and immunopathology, 2016 - Elsevier
Brucellosis is a livestock disease responsible for fetal loss due to abortions. Worldwide, this
disease has profound economic and social impact by reducing the ability of livestock …