Pathogen-imposed selection pressures have been paramount during human evolution.
Detecting such selection signatures in ancient and modern human genomes can thus help …

In the last three decades, genetic studies have played an increasingly important role in
exploring human history. They have helped to conclusively establish that anatomically …

Abstract The southern African indigenous Khoe-San populations harbor the most divergent
lineages of all living peoples. Exploring their genomes is key to understanding deep human …

Zoonotic spillover is a phenomenon characterized by the transfer of pathogens between
different animal species. Most human emerging infectious diseases originate from non …

African rainforests support exceptionally high biodiversity and host the world's largest
number of active hunter-gatherers [1–3]. The genetic history of African rainforest hunter …

Infections have imposed strong selection pressures throughout human evolution, making the
study of natural selection's effects on immunity genes highly complementary to disease …

Over the past few years several methodological and data-driven advances have greatly
improved our ability to robustly detect genomic signatures of selection in humans. New …

Africa is the continent with the greatest genetic diversity among humans and the level of
diversity is further enhanced by incorporating non-majority groups, which are often …

Immune response is one of the functions that have been more strongly targeted by natural
selection during human evolution. The evolutionary genetic dissection of the immune system …

Southern African indigenous groups, traditionally hunter-gatherers (San) and herders
(Khoekhoe), are commonly referred to as “Khoe-San” populations and have a long history in …