Recent advances in optical tweezers
JR Moffitt, YR Chemla, SB Smith… - Annu. Rev …, 2008 - annualreviews.org
It has been over 20 years since the pioneering work of Arthur Ashkin, and in the intervening
years, the field of optical tweezers has grown tremendously. Optical tweezers are now being …
years, the field of optical tweezers has grown tremendously. Optical tweezers are now being …
High-resolution, single-molecule measurements of biomolecular motion
WJ Greenleaf, MT Woodside… - Annu. Rev. Biophys …, 2007 - annualreviews.org
Many biologically important macromolecules undergo motions that are essential to their
function. Biophysical techniques can now resolve the motions of single molecules down to …
function. Biophysical techniques can now resolve the motions of single molecules down to …
Diverse paths to midcell: assembly of the bacterial cell division machinery
NW Goehring, J Beckwith - Current biology, 2005 - cell.com
At the heart of bacterial cell division is a dynamic ring-like structure of polymers of the tubulin
homologue FtsZ. This ring forms a scaffold for assembly of at least ten additional proteins at …
homologue FtsZ. This ring forms a scaffold for assembly of at least ten additional proteins at …
Loop extrusion: theory meets single-molecule experiments
EJ Banigan, LA Mirny - Current opinion in cell biology, 2020 - Elsevier
Chromosomes are organized as chromatin loops that promote segregation, enhancer-
promoter interactions, and other genomic functions. Loops were hypothesized to form by …
promoter interactions, and other genomic functions. Loops were hypothesized to form by …
[PDF][PDF] Mechanism of force generation of a viral DNA packaging motor
YR Chemla, K Aathavan, J Michaelis, S Grimes… - Cell, 2005 - cell.com
A large family of multimeric ATPases are involved in such diverse tasks as cell division,
chromosome segregation, DNA recombination, strand separation, conjugation, and viral …
chromosome segregation, DNA recombination, strand separation, conjugation, and viral …
Single-molecule analysis and engineering of DNA motors
Molecular motors are diverse enzymes that transduce chemical energy into mechanical
work and, in doing so, perform critical cellular functions such as DNA replication and …
work and, in doing so, perform critical cellular functions such as DNA replication and …
Connecting the dots: key insights on ParB for chromosome segregation from single-molecule studies
Bacterial cells require DNA segregation machinery to properly distribute a genome to both
daughter cells upon division. The most common system involved in chromosome and …
daughter cells upon division. The most common system involved in chromosome and …
Motor proteins and molecular motors: how to operate machines at the nanoscale
AB Kolomeisky - Journal of Physics: Condensed Matter, 2013 - iopscience.iop.org
Several classes of biological molecules that transform chemical energy into mechanical
work are known as motor proteins or molecular motors. These nanometer-sized machines …
work are known as motor proteins or molecular motors. These nanometer-sized machines …
Double-stranded DNA translocation: structure and mechanism of hexameric FtsK
FtsK is a DNA translocase that coordinates chromosome segregation and cell division in
bacteria. In addition to its role as activator of XerCD site-specific recombination, FtsK can …
bacteria. In addition to its role as activator of XerCD site-specific recombination, FtsK can …
KOPS: DNA motifs that control E. coli chromosome segregation by orienting the FtsK translocase
Bacterial chromosomes are organized in replichores of opposite sequence polarity. This
conserved feature suggests a role in chromosome dynamics. Indeed, sequence polarity …
conserved feature suggests a role in chromosome dynamics. Indeed, sequence polarity …