Atomistic simulations of pristine and nanoparticle reinforced hydrogels: A review

R Kumar, A Parashar - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
Hydrogel is a threedimensional crosslinked hydrophilic network that can imbibe a large
amount of water inside its structure (up to 99% of its dry weight). Due to their unique …

Intravitreal injectable hydrogels for sustained drug delivery in glaucoma treatment and therapy

KA Akulo, T Adali, MTG Moyo, T Bodamyali - Polymers, 2022 - mdpi.com
Glaucoma is extensively treated with topical eye drops containing drugs. However, the
retention time of the loaded drugs and the in vivo bioavailability of the drugs are highly …

Visco-hyperelastic constitutive modeling of strain rate sensitive soft materials

K Upadhyay, G Subhash, D Spearot - Journal of the Mechanics and Physics …, 2020 - Elsevier
A novel viscous dissipation potential is proposed for the visco-hyperelastic constitutive
modeling of short-time memory responses of soft materials, which can capture both linear …

Hyperelastic constitutive modeling of hydrogels based on primary deformation modes and validation under 3D stress states

K Upadhyay, G Subhash, D Spearot - International Journal of Engineering …, 2020 - Elsevier
In isotropic linear elasticity, a constitutive model calibrated using a single deformation mode
(eg, compression or tension or shear) is sufficient to describe a complex three-dimensional …

PEGDA hydrogel structure from semi-dilute concentrations: insights from experiments and molecular simulations

J Mercado-Montijo, DM Anstine, SJ Rukmani… - Soft Matter, 2022 - pubs.rsc.org
The efficacy of hydrogel materials used in biomedical applications is dependent on polymer
network topology and the structure of water-laden pore space. Hydrogel microstructure can …

Effect of the degree of polymerization and water content on the thermal transport phenomena in PEGDA hydrogel: a molecular-dynamics-based study

R Kumar, A Parashar - Physical Chemistry Chemical Physics, 2023 - pubs.rsc.org
A hydrogel is a 3D cross-linked polymer network that can absorb copious amounts of water
or biological fluid. Due to their biocompatibility and non-toxicity, hydrogels have a wide …

Dynamic responses of Ca-alginate/polyacrylamide hydrogels at high strain rates

Q Xue, Y Xiao, X Zhang, X Zhang, W Hong… - International Journal of …, 2024 - Elsevier
Many biological hydrogels possess remarkable mechanical performances under both quasi-
static and impact loadings, yet such mechanical robustness over a wide range of strain rates …

Physics-informed data-driven discovery of constitutive models with application to strain-rate-sensitive soft materials

K Upadhyay, JN Fuhg, N Bouklas… - Computational Mechanics, 2024 - Springer
A novel data-driven constitutive modeling approach is proposed, which combines the
physics-informed nature of modeling based on continuum thermodynamics with the benefits …

Validated tensile characterization of the strain rate dependence in soft materials

K Upadhyay, D Spearot, G Subhash - International Journal of Impact …, 2021 - Elsevier
A major obstacle in the accurate measurement of the dynamic tensile response of soft
materials is the issue of obtaining material response under simultaneous stress equilibrium …

Atomistic modelling and experimental study of tensile strength of nanocomposite hydrogel

R Kumar, A Chaurasia, A Tewari, A Parashar - International Journal of …, 2024 - Elsevier
Hydrogels are emerging as a potential material for tissue engineering. However, weak
mechanical strength is limiting its application in many diversified fields that includes tissue …