Human parechovirus: an increasingly recognized cause of sepsis-like illness in young infants

L Olijve, L Jennings, T Walls - Clinical microbiology reviews, 2018 - Am Soc Microbiol
Human parechovirus (HPeV) is increasingly being recognized as a potentially severe viral
infection in neonates and young infants. HPeV belongs to the family Picornaviridae and is …

Strategies to improve detection and management of human parechovirus infection in young infants

S Kadambari, H Harvala, P Simmonds… - The Lancet Infectious …, 2019 - thelancet.com
Human parechovirus infections are the second most common cause of viral meningitis in
children. These infections are most frequently seen in infants younger than 90 days. Clinical …

Parechovirus encephalitis and neurodevelopmental outcomes

PN Britton, RC Dale, MD Nissen, N Crawford… - …, 2016 - publications.aap.org
OBJECTIVE: We aimed to describe the clinical features and outcome of human parechovirus
(HPeV) encephalitis cases identified by the Australian Childhood Encephalitis (ACE) study …

Causes and clinical features of childhood encephalitis: a multicenter, prospective cohort study

PN Britton, RC Dale, CC Blyth, JE Clark… - Clinical Infectious …, 2020 - academic.oup.com
Background We aimed to determine the contemporary causes, clinical features, and short-
term outcome of encephalitis in Australian children. Methods We prospectively identified …

Parechovirus: an important emerging infection in young infants

PN Britton, CA Jones, K Macartney… - Medical Journal of …, 2018 - Wiley Online Library
Epidemics of human parechovirus (HPeV) causing disease in young children have occurred
every 2 years in Australia since 2013. HPeV genotype 3 caused the epidemic from late 2017 …

Human parechovirus type 3 infection: an emerging infection in neonates and young infants

Y Aizawa, R Izumita, A Saitoh - Journal of infection and chemotherapy, 2017 - Elsevier
Human parechoviruses (HPeVs) are RNA viruses that have characteristics similar to those of
enteroviruses and usually cause mild respiratory or gastrointestinal symptoms. Human …

Human parechovirus 3 in infants: expanding our knowledge of adverse outcomes

L Joseph, M May, M Thomas, C Smerdon… - The Pediatric …, 2019 - journals.lww.com
Background: Human parechovirus particularly genotype 3 (HPeV3) is an emerging infection
affecting predominantly young infants. The potential for neurologic sequelae in a vulnerable …

[HTML][HTML] An outbreak of severe infections among Australian infants caused by a novel recombinant strain of human parechovirus type 3

TM Nelson, P Vuillermin, J Hodge, J Druce… - Scientific Reports, 2017 - nature.com
Abstract Human parechovirus types 1–16 (HPeV1–16) are positive strand RNA viruses in
the family Picornaviridae. We investigated a 2015 outbreak of HPeV3 causing illness in …

High prevalence of developmental concern amongst infants at 12 months following hospitalised parechovirus infection

PN Britton, G Khandaker, A Khatami… - … of Paediatrics and …, 2018 - Wiley Online Library
Aim The human parechovirus (HPeV) is an increasingly recognised cause of sepsis and
central nervous system infection in young infants for which there are limited long‐term …

Outcome of routine cerebrospinal fluid screening for enterovirus and human parechovirus infection among infants with sepsis-like illness or meningitis in Cornwall, UK

P Chakrabarti, C Warren, L Vincent… - European journal of …, 2018 - Springer
Enteroviruses (EV) and human parechoviruses (HPeV) are known and emerging cause of
sepsis-like illnesses in infants; however, testing is not yet routine. We retrospectively …