Biotechnological routes based on lactic acid production from biomass

C Gao, C Ma, P Xu - Biotechnology advances, 2011 - Elsevier
Lactic acid, the most important hydroxycarboxylic acid, is now commercially produced by the
fermentation of sugars present in biomass. In addition to its use in the synthesis of …

Comparative analysis of the chemical and biochemical synthesis of keto acids

Z Luo, S Yu, W Zeng, J Zhou - Biotechnology advances, 2021 - Elsevier
Keto acids are essential organic acids that are widely applied in pharmaceuticals,
cosmetics, food, beverages, and feed additives as well as chemical synthesis. Currently …

Current advance in biological production of short-chain organic acid

L Sun, M Gong, X Lv, Z Huang, Y Gu, J Li, G Du… - Applied Microbiology …, 2020 - Springer
As natural metabolites, organic acids have been widely applied in food, pharmaceutical, and
bio-based materials industries. Particularly, the short-chain organic acids, including C2, C3 …

Protein and metabolic engineering for the production of organic acids

J Liu, J Li, H Shin, L Liu, G Du, J Chen - Bioresource Technology, 2017 - Elsevier
Organic acids are natural metabolites of living organisms. They have been widely applied in
the food, pharmaceutical, and bio-based materials industries. In recent years …

Microbial lactate utilization: enzymes, pathogenesis, and regulation

T Jiang, C Gao, C Ma, P Xu - Trends in microbiology, 2014 - cell.com
Lactate utilization endows microbes with the ability to use lactate as a carbon source.
Lactate oxidizing enzymes play key roles in the lactate utilization pathway. Various types of …

Stabilizing lactate production through repeated batch fermentation of food waste and waste activated sludge

X Xu, W Zhang, X Gu, Z Guo, J Song, D Zhu, Y Liu… - Bioresource …, 2020 - Elsevier
Bio-valorization of organic waste streams, such as food waste and waste activated sludge, to
lactic acid (LA) has recently drawn much attention. It offers an opportunity for resource …

Lactate utilization is regulated by the FadR-type regulator LldR in Pseudomonas aeruginosa

C Gao, C Hu, Z Zheng, C Ma, T Jiang, P Dou… - Journal of …, 2012 - Am Soc Microbiol
ABSTRACT NAD-independent l-lactate dehydrogenase (l-iLDH) and NAD-independent d-
lactate dehydrogenase (d-iLDH) activities are induced coordinately by either enantiomer of …

Genome sequence of the lactate-utilizing Pseudomonas aeruginosa strain XMG

C Gao, C Hu, C Ma, F Su, H Yu, T Jiang, P Dou… - 2012 - Am Soc Microbiol
Pseudomonas aeruginosa XMG, isolated from soil, utilizes lactate. Here we present a 6.45-
Mb assembly of its genome sequence. Besides the lactate utilization mechanism of the …

Genome sequence of the nonpathogenic Pseudomonas aeruginosa strain ATCC 15442

Y Wang, C Li, C Gao, C Ma, P Xu - Genome announcements, 2014 - Am Soc Microbiol
Pseudomonas aeruginosa ATCC 15442 is an environmental strain of the Pseudomonas
genus. Here, we present a 6.77-Mb assembly of its genome sequence. Besides giving …

Reconstruction of lactate utilization system in Pseudomonas putida KT2440: a novel biocatalyst for l-2-hydroxy-carboxylate production

Y Wang, M Lv, Y Zhang, X Xiao, T Jiang, W Zhang… - Scientific Reports, 2014 - nature.com
As an important method for building blocks synthesis, whole cell biocatalysis is hindered by
some shortcomings such as unpredictability of reactions, utilization of opportunistic …