The brown planthopper, Nilaparvata lugens is one of the most serious pests of rice, and
there is so far no effective way to manage this pest. However, RNA interference not only can …

The recent development of transposon and CRISPR-Cas9-based tools for manipulating the
fly genome in vivo promises tremendous progress in our ability to study developmental …

Manipulating gene function cell type-specifically is a common experimental goal in
Drosophila research and has been central to studies of neural development, circuit …

The subdivision of cell populations in compartments is a key event during animal
development. In Drosophila, the gene apterous (ap) divides the wing imaginal disc in dorsal …

Heparan sulfate proteoglycans (HSPGs) are composed of a core protein and
glycosaminoglycan (GAG) chains and serve as coreceptors for many growth factors and …

The regulation of the initiation of transcription by transcription factors is often assumed to be
dependent on specific recognition of DNA-binding sites and nonredundant. However, the …

During Drosophila embryonic nervous system development, neuroblasts express a
programmed cascade of five temporal transcription factors that govern the identity of cells …

The nervous system displays a daunting cellular diversity. Neuronal subtypes differ from
each other in several aspects, including their neurotransmitter expression and axon …

The extensive genetic regulatory flows underlying specification of different neuronal
subtypes are not well understood at the molecular level. The Nplp1 neuropeptide neurons in …

Enhancers are cis-regulatory elements that control most of the developmental and spatial
gene expression in eukaryotes. Genetic variation of enhancer sequences is known to …