Myosin heavy chain gene 7 (MYH7), a sarcomeric gene encoding the myosin heavy chain
(myosin-7), has attracted considerable interest as a result of its fundamental functions in …

Hypertrophic cardiomyopathy (HCM) is a genetic heart muscle disease that frequently
causes sudden cardiac death (SCD) among young adults. Several pathogenic mutations in …

Point mutations within sarcomeric proteins have been associated with altered function and
cardiomyopathy development. Difficulties remain, however, in establishing the pathogenic …

Hypertrophic cardiomyopathy (HCM) is an inherited disorder often caused by mutations to
sarcomeric genes. Many different HCM-associated TPM1 mutations have been identified but …

The role of genetic testing over the clinical and functional variables, including data from the
cardiopulmonary exercise test (CPET), in the hypertrophic cardiomyopathy (HCM) risk …

Familial dilated cardiomyopathy (DCM) is characterized by ventricular dilation and
depressed myocardial performance. It is a genetically heterogeneous disorder associated …

Descurainia sophia seeds (DS), Astragalus mongholicus (AM), and their formulas are widely
used to treat heart failure caused by various cardiac diseases in traditional Chinese …

The South Asian population, numbered at 1.8 billion, is estimated to comprise around 20%
of the global population and 1% of the American population, and has one of the highest …

Left ventricular non-compaction (cardiomyopathy)(LVN (C)) is a rare hereditary cardiac
condition, resulting from abnormal embryonic myocardial development. While it mostly …

Background Mutations in Myosin Binding Protein C (MYBPC3) are one of the most frequent
causes of cardiomyopathies in the world, but not much data are available in India. Methods …