[HTML][HTML] Maternally expressed gene 3 (MEG3): A tumor suppressor long non coding RNA

S Ghafouri-Fard, M Taheri - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Abstract Maternally expressed gene 3 (MEG3) is a long non-coding RNA (lncRNA) located
on chromosome 14q32. 3. Direct sequencing experiments have shown monoallelic …

Long non-coding RNAs (lncRNAs); roles in tumorigenesis and potentials as biomarkers in cancer diagnosis

S Najafi, SH Khatami, M Khorsand, Z Jamali… - Experimental cell …, 2022 - Elsevier
New research has indicated that long non-coding RNAs (lncRNAs) play critical roles in a
broad range of biological processes, including the pathogenesis of many complex human …

MEG3: an oncogenic long non-coding RNA in different cancers

A Al-Rugeebah, M Alanazi, NR Parine - Pathology & Oncology Research, 2019 - Springer
Long noncoding RNAs (lncRNAs) have recently considered as central regulators in diverse
biological processes and emerged as vital players controlling tumorigenesis. Several …

[HTML][HTML] lncRNA involvement in hepatocellular carcinoma metastasis and prognosis

M Abbastabar, M Sarfi, A Golestani, E Khalili - EXCLI journal, 2018 - ncbi.nlm.nih.gov
Eukaryotic lncRNAs are RNA molecules defined to be greater than 200 bp in length that are
not translated to a protein and operate through several mechanisms, including participating …

[HTML][HTML] A review of current evidence about lncRNA MEG3: A tumor suppressor in multiple cancers

J Xu, X Wang, C Zhu, K Wang - Frontiers in cell and developmental …, 2022 - frontiersin.org
Long non-coding RNA (lncRNA) maternally expressed gene 3 (MEG3) is a lncRNA located
at the DLK1-MEG3 site of human chromosome 14q32. 3. The expression of MEG3 in various …

Heterogeneous graph attention network based on meta-paths for lncrna–disease association prediction

X Zhao, X Zhao, M Yin - Briefings in bioinformatics, 2022 - academic.oup.com
Motivation: Discovering long noncoding RNA (lncRNA)–disease associations is a
fundamental and critical part in understanding disease etiology and pathogenesis. However …

LncRNA MEG3 functions as a ceRNA in regulating hepatic lipogenesis by competitively binding to miR-21 with LRP6

P Huang, F Huang, H Liu, T Zhang, M Yang, C Sun - Metabolism, 2019 - Elsevier
Background Hepatic lipogenesis dysregulation is essential for the development of non-
alcoholic fatty liver disease (NAFLD). Emerging evidence indicates the importance of the …

[HTML][HTML] Long non-coding RNA MEG3 promotes renal tubular epithelial cell pyroptosis by regulating the miR-18a-3p/GSDMD pathway in lipopolysaccharide-induced …

J Deng, W Tan, Q Luo, L Lin, L Zheng… - Frontiers in Physiology, 2021 - frontiersin.org
Background and Objective: Acute kidney injury (AKI) is a complication of sepsis. Pyroptosis
of gasdermin D (GSDMD)-mediated tubular epithelial cells (TECs) play important roles in …

[HTML][HTML] Long-noncoding RNAs (lncRNAs) in drug metabolism and disposition, implications in cancer chemo-resistance

Y Wang, Z Fang, M Hong, D Yang, W Xie - Acta Pharmaceutica Sinica B, 2020 - Elsevier
Drug metabolism is an orchestrated process in which drugs are metabolized and disposed
through a series of specialized enzymes and transporters. Alterations in the expression …

[HTML][HTML] LncRNA-MEG3 inhibits proliferation and metastasis by regulating miRNA-21 in gastric cancer

J Dan, J Wang, Y Wang, M Zhu, X Yang, Z Peng… - Biomedicine & …, 2018 - Elsevier
Gastric cancer (GC) is one of the most common malignant tumors with high mortality and
metastasis rate. Previous studies elucidated that Long non-coding RNA (LncRNA) MEG3 …