[HTML][HTML] Non-small cell lung cancer targeted therapy: drugs and mechanisms of drug resistance

J Wu, Z Lin - International journal of molecular sciences, 2022 - mdpi.com
The advent of precision medicine has brought light to the treatment of non-small cell lung
cancer (NSCLC), expanding the options for patients with advanced NSCLC by targeting …

[HTML][HTML] Tyrosine kinase receptors in oncology

J Esteban-Villarrubia, JJ Soto-Castillo, J Pozas… - International journal of …, 2020 - mdpi.com
Tyrosine kinase receptors (TKR) comprise more than 60 molecules that play an essential
role in the molecular pathways, leading to cell survival and differentiation. Consequently …

[PDF][PDF] Immunotherapy in the first-line treatment of NSCLC: current status and future directions in China

A Xiong, J Wang, C Zhou - Frontiers in oncology, 2021 - frontiersin.org
Lung cancer causes significant morbidity and mortality in China and worldwide. In China,
lung cancer accounts for nearly one-fourth of all cancer deaths. Non-small cell lung cancer …

Precision oncology: a clinical and patient perspective

UN Lassen, LE Makaroff, A Stenzinger, A Italiano… - Future …, 2021 - Taylor & Francis
Molecular characterization of tumors has shifted cancer treatment strategies away from
nonspecific cytotoxic treatment of histology-specific tumors toward targeting of actionable …

Therapeutic strategies for non-small cell lung cancer: Experimental models and emerging biomarkers to monitor drug efficacies

C Bourreau, L Treps, S Faure, D Fradin… - Pharmacology & …, 2023 - Elsevier
While new targeted therapies have considerably changed the treatment and prognosis of
non-small cell lung cancer (NSCLC), they are frequently unsuccessful due to primary or …

Novel targeted therapies for advanced non-small lung cancer

O Abughanimeh, A Kaur, B El Osta, AK Ganti - Seminars in Oncology, 2022 - Elsevier
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer accounting for
almost 80%–85% of all lung cancer cases. Unfortunately, more than half of the patients will …

[HTML][HTML] STARD3: a prospective target for cancer therapy

K Asif, L Memeo, S Palazzolo, Y Frión-Herrera, S Parisi… - Cancers, 2021 - mdpi.com
Simple Summary Alterations in cholesterol level play an important role in cancer
development. Lipid transfer proteins (LTPs) are involved in cholesterol distribution between …

Current treatment and novel insights regarding ROS1‐targeted therapy in malignant tumors

S Li, H Zhang, T Chen, X Zhang, G Shang - Cancer Medicine, 2024 - Wiley Online Library
Background The proto‐oncogene ROS1 encodes an intrinsic type I membrane protein of the
tyrosine kinase/insulin receptor family. ROS1 facilitates the progression of various …

[HTML][HTML] Consistency of recommendations for the diagnosis and treatment of non-small cell lung cancer: a systematic review

Z Zhang, S Yang, Y Ma, H Zhou, X Wu… - Translational Lung …, 2021 - ncbi.nlm.nih.gov
Background To systematically assess the consistency of recommendations regarding
diagnosis and treatment of non-small cell lung cancer (NSCLC) in clinical practice …

[HTML][HTML] TP53 Mutation Status and Biopsy Lesion Type Determine the Immunotherapeutic Stratification in Non-Small-Cell Lung Cancer

J Lu, R Zhong, Y Lou, M Hu, Z Yang, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Immunotherapy, a chemotherapy-free process, has emerged as a promising therapeutic
strategy to prolong the overall survival (OS) of patients with non-small-cell lung cancer …