Biliary atresia: pathology, etiology and pathogenesis

M Vij, M Rela - Future science OA, 2020 - Taylor & Francis
Biliary atresia is a progressive fibrosing obstructive cholangiopathy of the intrahepatic and
extrahepatic biliary system, resulting in obstruction of bile flow and neonatal jaundice …

Cholestatic liver diseases: a primer for generalists and subspecialists

MB Hilscher, PS Kamath, JE Eaton - Mayo Clinic Proceedings, 2020 - Elsevier
Cholestasis describes impairment in bile formation or flow which can manifest clinically with
fatigue, pruritus, and jaundice. The differential diagnosis of cholestatic liver diseases is …

Diagnostic accuracy of serum matrix metalloproteinase‐7 for biliary atresia

L Yang, Y Zhou, P Xu, R Mourya, H Lei, G Cao… - Hepatology, 2018 - journals.lww.com
Recent studies have indicated that a number of long noncoding RNAs (lncRNAs) are
dysregulated in hepatocellular carcinoma, while their aberrant expressions are associated …

Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia

C Lertudomphonwanit, R Mourya, L Fei… - Science translational …, 2017 - science.org
Biliary atresia is a progressive infantile cholangiopathy of complex pathogenesis. Although
early diagnosis and surgery are the best predictors of treatment response, current diagnostic …

Serum MMP-7 in the diagnosis of biliary atresia

J Jiang, J Wang, Z Shen, X Lu, G Chen, Y Huang… - …, 2019 - publications.aap.org
BACKGROUND: The overlapping features of biliary atresia (BA) and other neonatal
cholestasis with alternative causes (non-BA) have posed challenges for diagnosis. Matrix …

[HTML][HTML] Development and validation of novel diagnostic models for biliary atresia in a large cohort of Chinese patients

R Dong, J Jiang, S Zhang, Z Shen, G Chen, Y Huang… - …, 2018 - thelancet.com
Background & aims The overlapping features of biliary atresia (BA) and the other forms of
neonatal cholestasis (NC) with different causes (non-BA) has posed challenges for the …

Proteomics defines plasma biomarkers for the early diagnosis of biliary atresia

M Fu, Z Guo, Y Chen, JR Lamb, S Zhong… - Journal of Proteome …, 2024 - ACS Publications
Early diagnosis of biliary atresia (BA) is crucial for improving the chances of survival and
preserving the liver function of pediatric patients with BA. Herein, we performed proteomics …

Gut microbial profile in biliary atresia: a case‐control study

J Wang, T Qian, J Jiang, Y Yang, Z Shen… - Journal of …, 2020 - Wiley Online Library
Abstract Background and Aim Biliary atresia (BA) is a progressive fibro‐inflammatory
cholangiopathy with an unclear etiology. Various liver disorders are associated with an …

Dynamic analysis of serum MMP-7 and its relationship with disease progression in biliary atresia: a multicenter prospective study

S Chi, P Xu, P Yu, G Cao, H Wang, Y Ye, S Li… - Hepatology …, 2022 - Springer
Purpose We aimed to assess the dynamic changing trend of serum matrix metalloproteinase-
7 (MMP-7) in biliary atresia (BA) patients from diagnosis to LTx to further elucidate its clinical …

The difference of gut microbiome in different biliary diseases in infant before operation and the changes after operation

X Sun, Y Cai, W Dai, W Jiang, W Tang - BMC pediatrics, 2022 - Springer
Background Evidence supports an association between cholestatic liver disease and
changes in microbiome composition. Nevertheless, the identification of this special type of …