Ceramides are signals of fatty acid excess that accumulate when a cell's energetic needs
have been met and its nutrient storage has reached capacity. As these sphingolipids accrue …

Glycolipid balance is key to normal body function, and its alteration can lead to a variety of
diseases involving multiple organs and tissues. Glycolipid disturbances are also involved in …

The neurometabolic disorder succinic semialdehyde dehydrogenase (SSADH) deficiency
leads to great neurochemical imbalances and severe neurological manifestations. The …

Abstract Charcot-Marie-Tooth Disease (CMT) is a commonly inherited peripheral
polyneuropathy. Clinical manifestations for this disease include symmetrical distal …

Background There is a need for biomarkers of disease progression and therapeutic
response in multiple sclerosis (MS). This study aimed to identify cerebrospinal fluid (CSF) …

The mechanisms underlying lipid metabolic disorders in Parkinson's diseases (PD) remain
unclear. Weighted Gene Co-Expression Network Analysis (WGCNA) was conducted to …

Alcohol use disorder (AUD) is a diagnosis characterised by psychosocial behaviours
manifesting from chronic alcohol misuse. The effects of chronic alcohol misuse on the brain …