Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice
Abstract NMDA receptor (NMDAR) and GABA neuronal dysfunctions are observed in animal
models of autism spectrum disorders, but how these dysfunctions impair social cognition …
models of autism spectrum disorders, but how these dysfunctions impair social cognition …
Maturation of nucleus accumbens synaptic transmission signals a critical period for the rescue of social deficits in a mouse model of autism spectrum disorder
M Matthiesen, A Khlaifia, CFD Steininger Jr… - Molecular Brain, 2023 - Springer
Social behavior emerges early in development, a time marked by the onset of
neurodevelopmental disorders featuring social deficits, including autism spectrum disorder …
neurodevelopmental disorders featuring social deficits, including autism spectrum disorder …
Early cellular and synaptic changes in dopaminoceptive forebrain regions of juvenile mice following gestational exposure to valproate
CK Finszter, R Kemecsei, G Zachar… - Frontiers in …, 2023 - frontiersin.org
Gestational exposure of mice to valproic acid (VPA) is one currently used experimental
model for the investigation of typical failure symptoms associated with autism spectrum …
model for the investigation of typical failure symptoms associated with autism spectrum …
From hyposociability to hypersociability—the effects of psd-95 deficiency on the dysfunctional development of social behavior
Abnormal social behavior, including both hypo-and hypersociability, is often observed in
neurodevelopmental disorders such as autism spectrum disorders. However, the …
neurodevelopmental disorders such as autism spectrum disorders. However, the …
Dopaminergic neuromodulation of spike timing dependent plasticity in mature adult rodent and human cortical neurons
EL Louth, RL Jørgensen, AR Korshoej… - Frontiers in Cellular …, 2021 - frontiersin.org
Synapses in the cerebral cortex constantly change and this dynamic property regulated by
the action of neuromodulators such as dopamine (DA), is essential for reward learning and …
the action of neuromodulators such as dopamine (DA), is essential for reward learning and …
[HTML][HTML] Excess neonatal testosterone causes male-specific social and fear memory deficits in wild-type mice
P Quiñones-Labernik, KL Blocklinger, MR Bruce… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Neurodevelopmental disorders (ND) disproportionately affect males compared to females,
and Autism Spectrum Disorder (ASD) in particular exhibits a 4: 1 male bias. The biological …
and Autism Spectrum Disorder (ASD) in particular exhibits a 4: 1 male bias. The biological …