Synaptic plasticity forms and functions
JC Magee, C Grienberger - Annual review of neuroscience, 2020 - annualreviews.org
Synaptic plasticity, the activity-dependent change in neuronal connection strength, has long
been considered an important component of learning and memory. Computational and …
been considered an important component of learning and memory. Computational and …
Making sense of astrocytic calcium signals—from acquisition to interpretation
A Semyanov, C Henneberger, A Agarwal - Nature Reviews …, 2020 - nature.com
Astrocytes functionally interact with neurons and with other brain cells. Although not
electrically excitable, astrocytes display a complex repertoire of intracellular Ca2+ signalling …
electrically excitable, astrocytes display a complex repertoire of intracellular Ca2+ signalling …
[HTML][HTML] Targeted activation of hippocampal place cells drives memory-guided spatial behavior
The hippocampus is crucial for spatial navigation and episodic memory formation.
Hippocampal place cells exhibit spatially selective activity within an environment and have …
Hippocampal place cells exhibit spatially selective activity within an environment and have …
[HTML][HTML] A transcriptomic axis predicts state modulation of cortical interneurons
Transcriptomics has revealed that cortical inhibitory neurons exhibit a great diversity of fine
molecular subtypes,,,,–, but it is not known whether these subtypes have correspondingly …
molecular subtypes,,,,–, but it is not known whether these subtypes have correspondingly …
Fos ensembles encode and shape stable spatial maps in the hippocampus
In the hippocampus, spatial maps are formed by place cells while contextual memories are
thought to be encoded as engrams,,,,–. Engrams are typically identified by expression of the …
thought to be encoded as engrams,,,,–. Engrams are typically identified by expression of the …
The role of inhibitory circuits in hippocampal memory processing
L Topolnik, S Tamboli - Nature Reviews Neuroscience, 2022 - nature.com
GABAergic inhibitory circuits play an essential role in coordinating various hippocampal
functions. Several decades of work dedicated to a thorough characterization of hippocampal …
functions. Several decades of work dedicated to a thorough characterization of hippocampal …
GABAergic interneurons in the neocortex: from cellular properties to circuits
Cortical networks are composed of glutamatergic excitatory projection neurons and local
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …
Network abnormalities and interneuron dysfunction in Alzheimer disease
The function of neural circuits and networks can be controlled, in part, by modulating the
synchrony of their components' activities. Network hypersynchrony and altered oscillatory …
synchrony of their components' activities. Network hypersynchrony and altered oscillatory …
Hippocampal sharp wave‐ripple: A cognitive biomarker for episodic memory and planning
G Buzsáki - Hippocampus, 2015 - Wiley Online Library
Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …
mammalian brain. Their excitatory output affects a wide area of the cortex and several …
Entorhinal cortex directs learning-related changes in CA1 representations
C Grienberger, JC Magee - Nature, 2022 - nature.com
Learning-related changes in brain activity are thought to underlie adaptive behaviours,. For
instance, the learning of a reward site by rodents requires the development of an over …
instance, the learning of a reward site by rodents requires the development of an over …