Reproduction of different tissues using scaffolds and materials is a major element in
regenerative medicine. The regeneration of whole organs with decellularized extracellular …

Decellularization of natural tissues to produce extracellular matrix is a promising method for
three-dimensional scaffolding and for understanding microenvironment of the tissue of …

Organ transplantation is an effective treatment for chronic organ dysfunctioning conditions.
However, a dearth of available donor organs for transplantation leads to the death of …

Many studies, using pre-clinical models of SCI, have demonstrated the efficacy of
chondroitinase ABC as a treatment for spinal cord injury and this has been confirmed in …

Peripheral nerve injuries (PNI) are caused by a range of etiologies and result in a broad
spectrum of disability. While nerve autografts are the current gold standard for the …

A variety of surgical and non-surgical approaches have been used to address the impacts of
nervous system injuries, which can lead to either impairment or a complete loss of function …

Nowadays, the high incidence of peripheral nerve injuries and the low success ratio of
surgical treatments are driving research to the generation of novel alternatives to repair …

Background We hypothesize that adding sonication cycles to the process of
decellularization of cadaveric human peripheral nerves will increase the removal of cell …

Background Acellular nerve allografts (ANAs) have been established as promising
alternatives to autologous nerve grafts, which represent the reference standard. Our …

Background: Diffusion tensor tractography (DTT) has recently been shown to accurately
detect nerve injury and regeneration. This study assesses whether 7-tesla (7T) DTT imaging …