The array-comparative genomic hybridization (aCGH) and next generation sequence
technologies enable cost-efficient high resolution detection of DNA copy number variations …

Measurements using the high resolution array-comparative genomic hybridization (HR-
CGH) array are accompanied with large noise which strongly affects the estimates of the …

A big number of different estimators have been proposed during decades to detect the Copy
Number Alterations (CNA) in Deoxyribonucleic Acid (DNA) structures and indicate various …

Chromosomal structural changes in human body known as copy number alterations (CNAs)
are often associated with disease such as cancer. Therefore, accurate estimation of the …

Structural aberrations (SAs), gains or losses in large segments of genomes, are associated
with several genetic disorders. The SAs are commonly called the copy number alterations …

Jitter is inherent to the breakpoints of measured genome somatic copy number alterations
(SCNAs). Therefore, an analysis of jitter is required to reduce errors in the SCNA estimation …

Copy number alterations (CNAs) are hallmarks of cancer, which are now been routinely
measured by different techniques and used for diagnostic and prognostic purpose. Efficient …

Chromosomal structural changes known as copy number alterations-aberrations (CNAs)
result in gains or losses in copies of deoxyribonucleic acid sections, which are typically …

Structural aberrations (SAs), gains or losses in large segments of genomes, are associated
with several genetic disorders. The SAs are commonly called the copy number alterations …

We analyze and approximate the jitter distribution function in the breakpoints of the
measured genome copy number alterations (CNAs). The CNAs measured using the high …