This review provides a practical guide to myeloperoxidase (MPO) and presents to the reader
the diversity of its presence in biology. The review provides a historical background, from …

Increased oxidative stress and apoptosis have been implicated in the cardiotoxicity that
limits the clinical use of cisplatin as an anti-tumoral drug. Our study was conducted to …

Background Doxorubicin (DOX) is commonly used in the treatment of many types of cancers
but its cardiotoxicity is limiting its clinical use. Beyond its anticoagulant action, enoxaparin …

Cisplatin is one of the most potent chemotherapeutic antitumor drugs. Oxidative stress has
been proven to be involved in cisplatin-induced toxicity. Therefore, the present study was …

In the present study, we explored SA's activity against DOX‐induced cardiotoxicity and
revealed its underlying mechanisms. Male Wistar rats (weight, 190‐210g; n= 6) were …

The main adverse effect of doxorubicin is cardiotoxicity. Oxidative stress and apoptosis
induction have been suggested as mechanisms involved in its cardiotoxicity. In this study …

Erdosteine was introduced in the market as a mucolytic agent for chronic pulmonary
diseases more than 10 years ago. The drug contains two blocked sulphydryl groups one of …

Adriamycin is a potent anticancer agent, its clinical use is limited for its marked cardiotoxicity
and nephrotoxicity. The present study aimed to investigate the possible protective role of the …

The possible protective effects of resveratrol (RVT) against cardiotoxicity were investigated
in Wistar albino rats treated with saline, saline+ doxorubicin (DOX; 20 mg/kg) or RVT (10 …

Oleuropein, a natural phenolic compound, prevents acute doxorubicin (DXR)-induced
cardiotoxicity but there is no evidence regarding its role in chronic DXR-induced …