IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies
A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …
mediating innate and adaptive immunity and multiple physiological processes, including …
Sex differences in innate and adaptive immunity impact fetal, placental, and maternal health
The differences between males and females begin shortly after birth, continue throughout
prenatal development, and eventually extend into childhood and adult life. Male embryos …
prenatal development, and eventually extend into childhood and adult life. Male embryos …
[HTML][HTML] Pre-pregnancy obesity is associated with greater systemic inflammation and increased risk of antenatal depression
Background Pre-pregnancy obesity is an emerging risk factor for perinatal depression.
However, the underlying mechanisms remain unclear. We investigated the association …
However, the underlying mechanisms remain unclear. We investigated the association …
Immune alterations in recurrent implantation failure
N Mukherjee, R Sharma, D Modi - American Journal of …, 2023 - Wiley Online Library
A failure to achieve pregnancy after three or more embryo transfer cycles with high‐quality
blastocysts is referred to as recurrent implantation failure (RIF). RIF can be due to altered …
blastocysts is referred to as recurrent implantation failure (RIF). RIF can be due to altered …
Human plasma proteome during normal pregnancy
The human plasma proteome is underexplored despite its potential value for monitoring
health and disease. Herein, using a recently developed aptamer-based platform, we profiled …
health and disease. Herein, using a recently developed aptamer-based platform, we profiled …
Cross-generational impact of innate immune memory following pregnancy complications
Pregnancy complications can have long-term negative effects on the health of the affected
mothers and their children. In this review, we highlight the underlying inflammatory …
mothers and their children. In this review, we highlight the underlying inflammatory …
Breast cancers co-opt normal mechanisms of tolerance to promote immune evasion and metastasis
Normal developmental processes, such as those seen during embryonic development and
postpartum mammary gland involution, can be reactivated by cancer cells to promote …
postpartum mammary gland involution, can be reactivated by cancer cells to promote …
ALASCA: an R package for longitudinal and cross-sectional analysis of multivariate data by ASCA-based methods
AH Jarmund, TS Madssen… - Frontiers in Molecular …, 2022 - frontiersin.org
The increasing availability of multivariate data within biomedical research calls for
appropriate statistical methods that can describe and model complex relationships between …
appropriate statistical methods that can describe and model complex relationships between …
Biomarkers of environmental enteric dysfunction and adverse birth outcomes: An observational study among pregnant women living with HIV in Tanzania
Background Environmental enteric dysfunction (EED) may contribute to adverse birth
outcomes in low-resource settings. We examined the associations of EED biomarkers with …
outcomes in low-resource settings. We examined the associations of EED biomarkers with …
Setting a stage: Inflammation during preeclampsia and postpartum
O Herrock, E Deer, B LaMarca - Frontiers in Physiology, 2023 - frontiersin.org
Preeclampsia (PE) is a leading cause of maternal and fetal mortality worldwide. The immune
system plays a critical role in normal pregnancy progression; however, inappropriate …
system plays a critical role in normal pregnancy progression; however, inappropriate …