Many active pharmaceutical ingredients show low oral bioavailability due to factors such as
poor solubility and physical and chemical instability. The formation of inclusion complexes …

Cyclodextrins (CDs) and cyclodextrin (CD)-based polymers are well-known complexing
agents. One of their distinctive features is to increase the quantity of a drug in a solution or …

Cancer has been a threat to human health, so its treatment is a huge challenge to the
present medical field. One of commonly used methods is the controlled release of anticancer …

Low water solubility is the main hindrance in the growth of pharmaceutical industry.
Approximately 90% of newer molecules under investigation for drugs and 40% of novel …

Objective The anticancer efficacy of orally administered chemotherapeutics is often
constrained by low intestinal membrane permeability and oral bioavailability. In this context …

Spray drying is an important technology that is fast, simple, reproducible, and scalable. It has
a wide application range, that is, in food, chemicals, and encapsulation of pharmaceuticals …

There is an urgent need to develop safer and more effective modalities for the treatment of
numerous pathologies due to the increasing rates of drug resistance, undesired side effects …

The purpose of this study was to investigate the impact of anticancer drug erlotinib-randomly
methylated-β-cyclodextrin complex (ERL-RAMEB CD) on drug solubility and dissolution …

The supramolecular complexation of doxepin (DOX) with cucurbit [7] uril (CB7) was
investigated in aqueous solution. The results indicated the formation of a host–guest …

Anti-cancer drugs are mostly limited in their use due to poor physicochemical and
biopharmaceutical properties. Their lower solubility is the most common hurdle limiting their …