[HTML][HTML] A comparative analysis of mycobacterial ribonucleases: Toward a therapeutic novel drug target
LK Jaiswal, RK Singh, T Nayak, A Kakkar… - Infection, Genetics and …, 2024 - Elsevier
Bacterial responses to continuously changing environments are addressed through
modulation of gene expression at the level of transcription initiation, RNA processing and/or …
modulation of gene expression at the level of transcription initiation, RNA processing and/or …
The Structural and Molecular Mechanisms of Mycobacterium tuberculosis Translational Elongation Factor Proteins
N Fang, L Wu, S Duan, J Li - Molecules, 2024 - mdpi.com
Targeting translation factor proteins holds promise for developing innovative anti-
tuberculosis drugs. During protein translation, many factors cause ribosomes to stall at …
tuberculosis drugs. During protein translation, many factors cause ribosomes to stall at …
Harnessing the potential of lipid nanoparticles for the delivery of chemically modified siRNA to combat hepatic adenovirus infection
QTH Shubhra, AKMM Alam - Molecular Therapy-Nucleic Acids, 2023 - cell.com
Lipid nanoparticles (LNPs) represent a highly versatile class of drug delivery system (DDS)
for both small-molecule drugs and nucleic acids, thus presenting a promising avenue for …
for both small-molecule drugs and nucleic acids, thus presenting a promising avenue for …
New option: targeting RNase J and RNase HI in the fight against multi-drug-resistant tuberculosis
P Khadka, J Thapaliya - Annals of Medicine and Surgery, 2024 - journals.lww.com
Tuberculosis remains a recalcitrant global health issue despite being discovered a century
ago and powerful antibiotics being developed. 10.6 million cases of active tuberculosis were …
ago and powerful antibiotics being developed. 10.6 million cases of active tuberculosis were …