Neuroimaging studies of neuropsychiatric behavior biomarkers across spectrum disorders
are typically based on diagnosis, thus failing to account for the heterogeneity of multi …

Magnetic resonance spectroscopy (MRS) provides unique information about the
neurobiological substrates of brain function in health and disease. However, many of the …

Mutations in isocitrate dehydrogenases 1 and 2 (IDH1 and IDH2) have been shown to be
present in most World Health Organization grade 2 and grade 3 gliomas in adults. These …

Deactivation of the human brain's default mode network (DMN) is regarded as suppression
of endogenous activity to support exogenous task-related processes. This phenomenon has …

Advances in functional magnetic resonance spectroscopy (fMRS) have enabled the
quantification of activity-dependent changes in neurotransmitter concentrations in vivo …

Purpose In vivo magnetic resonance spectroscopy (MRS) is the only technique capable of
non‐invasively assessing metabolite concentrations in the brain. The lack of alternative …

2‐Hydroxyglutarate (2HG) is produced in gliomas with mutations of isocitrate
dehydrogenase (IDH) 1 and 2. The 1H resonances of the J‐coupled spins of 2HG are …

Abstract Models of healthy brain function and psychiatric conditions assume that excitatory
and inhibitory activity are balanced in the human brain at multiple spatial and temporal …

Recent studies suggest that the interaction between presbycusis and cognitive impairment
may be partially explained by the cognitive-ear link. However, the underlying …

It is unclear whether alterations in cerebral pH underlie Alzheimer's disease (AD) and other
dementias. We performed proton spectroscopy after oral administration of histidine in …