The schizophrenia syndrome, circa 2024: What we know and how that informs its nature

R Tandon, H Nasrallah, S Akbarian… - Schizophrenia …, 2024 - Elsevier
With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

Biological hypotheses, risk factors, and biomarkers of schizophrenia

Z Fišar - Progress in Neuro-Psychopharmacology and …, 2023 - Elsevier
Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …

Neuroimaging in schizophrenia

MS Keshavan, G Collin, S Guimond… - … Clinics of North …, 2019 - pmc.ncbi.nlm.nih.gov
Psychotic disorders are mental illnesses characterized by difficulties in reality testing1.
Schizophrenia is a severe and chronic psychotic disorder with a life time prevalence of …

[HTML][HTML] Novel approaches in schizophrenia-from risk factors and hypotheses to novel drug targets

M Ľupták, D Michaličková, Z Fišar… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Schizophrenia is a severe psychiatric disorder characterized by emotional, behavioral and
cognitive disturbances, and the treatment of schizophrenia is often complicated by …

Functional connectome organization predicts conversion to psychosis in clinical high-risk youth from the SHARP program

G Collin, LJ Seidman, MS Keshavan, WS Stone… - Molecular …, 2020 - nature.com
The emergence of prodromal symptoms of schizophrenia and their evolution into overt
psychosis may stem from an aberrant functional reorganization of the brain during …

[HTML][HTML] Brain functional connectivity data enhance prediction of clinical outcome in youth at risk for psychosis

G Collin, A Nieto-Castanon, ME Shenton… - NeuroImage: Clinical, 2020 - Elsevier
The first episode of psychosis is typically preceded by a prodromal phase with subthreshold
symptoms and functional decline. Improved outcome prediction in this stage is needed to …

Baseline structural and functional magnetic resonance imaging predicts early treatment response in schizophrenia with radiomics strategy

LB Cui, YF Fu, L Liu, XS Wu, YB Xi… - European Journal of …, 2021 - Wiley Online Library
Multimodal neuroimaging features provide opportunities for accurate classification and
personalized treatment options in the psychiatric domain. This study aimed to investigate …

Functional connectome hierarchy in schizotypy and its associations with expression of schizophrenia-related genes

D Dong, Y Wang, F Zhou, X Chang, J Qiu… - Schizophrenia …, 2025 - academic.oup.com
Abstract Background and Hypothesis Schizotypy has been conceptualized as a continuum
of symptoms with marked genetic, neurobiological, and sensory-cognitive overlaps to …

Connectome dysfunction in patients at clinical high risk for psychosis and modulation by oxytocin

C Davies, D Martins, O Dipasquale… - Molecular …, 2024 - nature.com
Abnormalities in functional brain networks (functional connectome) are increasingly
implicated in people at Clinical High Risk for Psychosis (CHR-P). Intranasal oxytocin, a …

Brain Abnormalities in Schizophrenia: A Comparative Imagistic Study

PS Petric, P Ifteni, AA Miron, G Sechel, A Teodorescu - Medicina, 2024 - mdpi.com
Background and Objectives: Neuroimaging reveals a link between psychiatric conditions
and brain structural–functional changes, prompting a paradigm shift in viewing …