Microwave-assisted synthesis of numerous bioactive scaffolds has gained much attention of
late in organic chemistry. Most of the heterocyclic rings can be synthesized using the …

Steroids modification for improving their biological activities is one of the most efficient and
fruitful methods to develop novel medicines. Steroids with aza-heterocycles attaching to the …

Background Although accumulating evidence suggests that the crosstalk between malignant
cells and cancer-associated fibroblasts (CAFs) actively contributes to tumour growth and …

Abstract Argentatins A–C (1–3), the major cycloartane-type triterpenoids of guayule resin, a
byproduct of commercial rubber production, were converted into their pyrimidine (7–12) …

Background Multidrug resistance is a common reason behind the failure of chemotherapy.
Even if the therapy is effective, serious adverse effects might develop due to the low …

Steroidal heterocyclic compounds constitute interesting and promising scaffolds for drug
discovery as they have displayed diverse chemical reactivity and several types of biological …

Steroids are components of cell membranes, signaling molecules and are a type of
secondary metabolites as a result of their high impact of biological significance. The present …

One of the main directions of steroid research is the preparation of modified derivatives in
which, in addition to changes in physicochemical properties, receptor binding is significantly …

The review systematizes and summarizes data on the synthesis of structurally diverse cyclic
ureas published over the last 10 years. Saturated and unsaturated monocyclic ureas, as well …

Reports on structural diversification of steroids by means of multicomponent reactions
(MCRs) have significantly increased over the last decade. This review covers the most …