Rapidly growing demand of functional polymers in various interdisciplinary areas of
research has accentuated the need for modern synthetic tools to develop advanced …

Crosslinking mass spectrometry (crosslinking-MS) is a versatile tool providing structural
insights into protein conformation and protein-protein interactions. Its medium-resolution …

Isobaric stable isotope labeling using, for example, tandem mass tags (TMTs) is increasingly
being applied for large-scale proteomic studies. Experiments focusing on proteoform …

A two-step zero-length crosslinking procedure for studying protein-protein complexes has
been developed. One component of a complex is briefly incubated with 1-ethyl-3-(3 …

A method for fast and simple covalent immobilization of proteins to a carboxymethyldextran-
modified gold surface intended for surface plasmon resonance sensors is described. The …

Electrochemical (EC) sensing approaches have exploited the use of carbon nanotubes
(CNTs) as electrode materials owing to their unique structures and properties to provide …

Efficient and site‐specific modification of native peptides and proteins is desirable for
synthesizing antibody‐drug conjugates as well as for constructing chemically modified …

Abstract Structure elucidation of tertiary or quaternary protein structures by chemical cross‐
linking and mass spectrometry (MS) has recently gained importance. To locate the cross …

Nanoparticles provide an ideal remedy to the usually contradictory issues encountered in
the optimization of immobilized enzymes: minimum diffusional limitation, maximum surface …

N-Hydroxysuccinimide (NHS) ester terminal groups are commonly used to covalently couple
amine-containing biomolecules (eg, proteins and peptides) to surfaces via amide linkages …