Solid tumor malignancies including breast, lung and prostate carcinomas are considered to
be angiogenesis dependent. Tumor angiogenesis is often mediated by hypoxia secondary …

Genetic alterations that lead to loss or changes in tumour-suppressor genes are known to
contribute to oral carcinogenesis. Traditional molecular methods to detect such losses have …

Dysregulation of gene expression is a frequent occurrence in oral squamous cell carcinoma
(OSCC). However, accumulating evidence suggests that in contrast to genetics, epigenetic …

Squamous cell carcinoma of the oral region (OSCC) is one of the most common and highly
aggressive malignancies worldwide, despite the fact that significant results have been …

Epigenic modifications, mainly DNA methylation and acetylation, are recognized as the main
mechanisms contributing to the malignant phenotype. Acetylation and deacetylation are …

US7820378B2 - Fragmentation-based methods and systems for sequence variation detection
and discovery - Google Patents US7820378B2 - Fragmentation-based methods and systems …

Methylation of DNA at 5-position of cytosine, catalyzed by DNA methyltransferases, is the
predominant epigenetic modification in mammals. Aberrations in methylation play a causal …

Aberrant epigenetic silencing of tumor suppressor genes by promoter DNA
hypermethylation and histone deacetylation plays an important role in the pathogenesis of …

Maspin, a non-inhibitory member of the serine protease inhibitor superfamily, has been
characterized as a tumor suppressor gene in multiple cancer types. Among the established …

Simple Summary This comprehensive review focuses on the role of epigenetics in oral
squamous cell carcinoma (OSCC), a prevalent type of oral cancer. The review highlights the …