Optical sensors represent a vitally important class of analytical tools that have been used to
provide chemical information ranging from analyte concentration and binding kinetics to …

Increasing interest has been paid to label-free biosensors in recent years. Among them,
refractive index (RI) optical biosensors enable high density and the chip-scale integration of …

Utilizing its integrated camera as a spectrometer, we demonstrate the use of a smartphone
as the detection instrument for a label-free photonic crystal biosensor. A custom-designed …

We demonstrate a surface-enhanced Raman scattering (SERS) substrate consisting of a
closely spaced metal nanodome array fabricated on flexible plastic film. We used a low-cost …

Conspectus Fluorescence technology pervades all areas of chemical and biological
sciences. In recent years, it is being realized that traditional fluorescence can be enriched in …

We have demonstrated the proof-of-concept of a label-free fluorescence quantitative
detection platform based on gold nanoparticle (AuNP) enhancement intrinsic fluorescence …

Biosensor technologies that have been primarily used in the past for characterizing
biomolecular interactions are now being used to develop new approaches for performing …

Photonic crystal surfaces that are designed to function as wavelength-selective optical
resonators have become a widely adopted platform for label-free biosensing, and for …

A form of microscopy that utilizes a photonic crystal biosensor surface as a substrate for cell
attachment enables label-free, quantitative, submicron resolution, time-resolved imaging of …

We review the development and application of nanostructured photonic crystal surfaces and
a hyperspectral reflectance imaging detection instrument which, when used together …