The role of goblet cells and mucus in intestinal homeostasis
JK Gustafsson, MEV Johansson - Nature reviews Gastroenterology & …, 2022 - nature.com
The intestinal tract faces numerous challenges that require several layers of defence. The
tight epithelium forms a physical barrier that is further protected by a mucus layer, which …
tight epithelium forms a physical barrier that is further protected by a mucus layer, which …
The microbiome and gut homeostasis
JY Lee, RM Tsolis, AJ Bäumler - Science, 2022 - science.org
Changes in the composition of the gut microbiota are associated with many human
diseases. So far, however, we have failed to define homeostasis or dysbiosis by the …
diseases. So far, however, we have failed to define homeostasis or dysbiosis by the …
Intestinal mucus and their glycans: A habitat for thriving microbiota
AS Luis, GC Hansson - Cell Host & Microbe, 2023 - cell.com
The colon mucus layer is organized with an inner colon mucus layer that is impenetrable to
bacteria and an outer mucus layer that is expanded to allow microbiota colonization. A major …
bacteria and an outer mucus layer that is expanded to allow microbiota colonization. A major …
The gut microbiota and its biogeography
G McCallum, C Tropini - Nature Reviews Microbiology, 2024 - nature.com
Biogeography is the study of species distribution and diversity within an ecosystem and is at
the core of how we understand ecosystem dynamics and interactions at the macroscale. In …
the core of how we understand ecosystem dynamics and interactions at the macroscale. In …
Bile acids as modulators of gut microbiota composition and function
AB Larabi, HLP Masson, AJ Bäumler - Gut Microbes, 2023 - Taylor & Francis
Changes in the composition of gut-associated microbial communities are associated with
many human illnesses, but the factors driving dysbiosis remain incompletely understood …
many human illnesses, but the factors driving dysbiosis remain incompletely understood …
Inflammatory and microbiota-related regulation of the intestinal epithelial barrier
G Barbara, MR Barbaro, D Fuschi, M Palombo… - Frontiers in …, 2021 - frontiersin.org
The intestinal epithelial barrier (IEB) is one of the largest interfaces between the
environment and the internal milieu of the body. It is essential to limit the passage of harmful …
environment and the internal milieu of the body. It is essential to limit the passage of harmful …
Weaning stress and intestinal health of piglets: A review
X Tang, K Xiong, R Fang, M Li - Frontiers in immunology, 2022 - frontiersin.org
Weaning is considered to be one of the most critical periods in pig production, which is
related to the economic benefits of pig farms. However, in actual production, many piglets …
related to the economic benefits of pig farms. However, in actual production, many piglets …
Mucus barrier, mucins and gut microbiota: the expected slimy partners?
The gastrointestinal tract is often considered as a key organ involved in the digestion of food
and providing nutrients to the body for proper maintenance. However, this system is …
and providing nutrients to the body for proper maintenance. However, this system is …
Randomized controlled-feeding study of dietary emulsifier carboxymethylcellulose reveals detrimental impacts on the gut microbiota and metabolome
Background & Aims Epidemiologic and murine studies suggest that dietary emulsifiers
promote development of diseases associated with microbiota dysbiosis. Although the …
promote development of diseases associated with microbiota dysbiosis. Although the …
Host–microbiota interactions in inflammatory bowel disease
The mammalian intestine is colonized by trillions of microorganisms that have co-evolved
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …