Vaccinomics: Paving the Way for Personalized Immunization

LN Al-Eitan, MFM ElMotasem, IY Khair… - Current …, 2024 - benthamdirect.com
Vaccines are one of the most important medical advancements in human history. They have
been successfully used to control and limit the spread of many of the lethal diseases that …

Integrated analysis of mRNA-seq and miRNA-seq to identify c-MYC, YAP1 and miR-3960 as major players in the anticancer effects of caffeic acid phenethyl ester in …

F Mo, Y Luo, D Fan, H Zeng, Y Zhao, M Luo… - Current Gene …, 2020 - ingentaconnect.com
Background: Caffeic Acid Phenethyl Ester (CAPE), an active extract of propolis, has recently
been reported to have broad applications in various cancers. However, the effects of CAPE …

Subtractive genomics and comparative metabolic pathways profiling revealed novel drug targets in Ureaplasma urealyticum

L Chen, Z Zhang, Q Zeng, W Wang, H Zhou… - Frontiers in …, 2024 - frontiersin.org
Introduction Ureaplasma urealyticum is a commensal organism found in the human lower
genitourinary tract, which can cause urogenital infections and complications in susceptible …

In vitro and in silico perspectives to explain anticancer activity of a novel syringic acid analog ((4-(1H-1, 3-benzodiazol-2-yl)-2, 6-dimethoxy phenol)) through apoptosis …

S Cheemanapalli, C Palaniappan, Y Mahesh… - Computers in Biology …, 2023 - Elsevier
Syringic acid (SA) is an active carcinogenesis inhibitor; however, the low bioavailability and
unstable functional groups hinder its activity. Here, a chemically synthesized novel SA …

Application of Organoids in Carcinogenesis Modeling and Tumor Vaccination

Z Wang, S Zhao, X Lin, G Chen, J Kang, Z Ma… - Frontiers in …, 2022 - frontiersin.org
Organoids well recapitulate organ-specific functions from their tissue of origin and remain
fundamental aspects of organogenesis. Organoids are widely applied in biomedical …

Predictive Modeling of Multiplex Chemical Phenomics for Novel Cells and Patients: Applied to Personalized Alzheimer's Disease Drug Repurposing

Q Liu, Y Qiu, L Xie - bioRxiv, 2021 - biorxiv.org
Chemical phenomics which measures multiplex chemical-induced phenotypic response of
cells or patients, particularly dose-dependent transcriptomics and drug-response curves …

Date Palm (Phoenix dactylifera L.) Chloroplast Genome

MK Azim - The Date Palm Genome, Vol. 1: Phylogeny …, 2021 - Springer
The chloroplast is a significant organelle of autotrophic cells which contains an autonomous,
double-stranded, circular DNA molecule (cpDNA) known as the chloroplast genome. It …

[图书][B] Using Emerging Next-Generation Sequencing Technologies to Enhance the Lifecycle of Biopharmaceuticals

IS Shamie - 2022 - search.proquest.com
Biopharmaceuticals are emerging as a promising avenue for treating a range of diseases,
and bringing down the costs of production, as well as monitoring the response to treatment …

[HTML][HTML] Benefits of Automation

S Söllner - dispendix.com
Conclusion The integration of NGS liquid dispensing automation into library preparation
workflows significantly enhances efficiency, accuracy, safety, and cost-effectiveness …

[引用][C] Current Pharmaceutical Innovations and Implementation of In-silico Models with Designs of Promising Lead Molecules and Formulations

S Nandi, H Roy - Current Pharmaceutical Design, 2019 - ingentaconnect.com
Indentification, design, screening and development of the lead-like drug molecule and
pharmaceutical product need plenty of time, human resources and expenditure. The …