Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics
L Migliore, F Coppedè - Nature Reviews Neurology, 2022 - nature.com
With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …
Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders
LG Costa, TB Cole, K Dao, YC Chang, J Coburn… - Pharmacology & …, 2020 - Elsevier
Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …
cardiovascular diseases, may also negatively affect the brain and contribute to central …
Involvement of astrocytes in Alzheimer's disease from a neuroinflammatory and oxidative stress perspective
RE González-Reyes, MO Nava-Mesa… - Frontiers in molecular …, 2017 - frontiersin.org
Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …
humans, but still no curative treatment has been developed. Although many explicative …
Exposure to air pollution in relation to risk of dementia and related outcomes: an updated systematic review of the epidemiological literature
Background: Dementia is a devastating neurologic condition that is common in older adults.
We previously reviewed the epidemiological evidence examining the hypothesis that long …
We previously reviewed the epidemiological evidence examining the hypothesis that long …
[HTML][HTML] A critical review of the epidemiological evidence of effects of air pollution on dementia, cognitive function and cognitive decline in adult population
JM Delgado-Saborit, V Guercio, AM Gowers… - Science of the Total …, 2021 - Elsevier
Dementia is arguably the most pressing public health challenge of our age. Since dementia
does not have a cure, identifying risk factors that can be controlled has become paramount …
does not have a cure, identifying risk factors that can be controlled has become paramount …
Rationale for a multi-factorial approach for the reversal of cognitive decline in Alzheimer's disease and MCI: a review
RV Rao, KG Subramaniam, J Gregory… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative disease
typically characterized by memory loss, personality changes, and a decline in overall …
typically characterized by memory loss, personality changes, and a decline in overall …
Olfactory dysfunction in neurodegenerative diseases: is there a common pathological substrate?
RL Doty - The Lancet Neurology, 2017 - thelancet.com
In patients with neurodegenerative diseases, there is a spectrum of smell dysfunction
ranging from severe loss, as seen in Alzheimer's disease and Parkinson's disease, to …
ranging from severe loss, as seen in Alzheimer's disease and Parkinson's disease, to …
Are noise and air pollution related to the incidence of dementia? A cohort study in London, England
IM Carey, HR Anderson, RW Atkinson, SD Beevers… - BMJ open, 2018 - bmjopen.bmj.com
Objective To investigate whether the incidence of dementia is related to residential levels of
air and noise pollution in London. Design Retrospective cohort study using primary care …
air and noise pollution in London. Design Retrospective cohort study using primary care …
The therapeutic potential of metformin in neurodegenerative diseases
C Rotermund, G Machetanz… - Frontiers in endocrinology, 2018 - frontiersin.org
The search for treatments for neurodegenerative diseases is a major concern in light of
today's aging population and an increasing burden on individuals, families, and society …
today's aging population and an increasing burden on individuals, families, and society …
Oxidant/antioxidant imbalance in Alzheimer's disease: therapeutic and diagnostic prospects
J Wojsiat, KM Zoltowska… - Oxidative medicine …, 2018 - Wiley Online Library
Alzheimer's disease (AD) is the most common cause of dementia and a great
socioeconomic burden in the aging society. Compelling evidence demonstrates that …
socioeconomic burden in the aging society. Compelling evidence demonstrates that …