The role of inflammation in cardiovascular disease

MY Henein, S Vancheri, G Longo… - International journal of …, 2022 - mdpi.com
Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

Endothelial cell dysfunction and the pathobiology of atherosclerosis

MA Gimbrone Jr, G García-Cardeña - Circulation research, 2016 - Am Heart Assoc
Dysfunction of the endothelial lining of lesion-prone areas of the arterial vasculature is an
important contributor to the pathobiology of atherosclerotic cardiovascular disease …

[HTML][HTML] Uncertainty and stress: Why it causes diseases and how it is mastered by the brain

A Peters, BS McEwen, K Friston - Progress in neurobiology, 2017 - Elsevier
The term 'stress'–coined in 1936–has many definitions, but until now has lacked a
theoretical foundation. Here we present an information-theoretic approach–based on the …

Wall shear stress and its role in atherosclerosis

M Zhou, Y Yu, R Chen, X Liu, Y Hu, Z Ma… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis (AS) is the major form of cardiovascular disease and the leading cause of
morbidity and mortality in countries around the world. Atherosclerosis combines the …

Expert recommendations on the assessment of wall shear stress in human coronary arteries: existing methodologies, technical considerations, and clinical …

F Gijsen, Y Katagiri, P Barlis, C Bourantas… - European heart …, 2019 - academic.oup.com
Expert recommendations on the assessment of wall shear stress in human coronary arteries:
existing methodologies, technical considerations, and clinical applications | European Heart …

SimVascular: an open source pipeline for cardiovascular simulation

A Updegrove, NM Wilson, J Merkow, H Lan… - Annals of biomedical …, 2017 - Springer
Patient-specific cardiovascular simulation has become a paradigm in cardiovascular
research and is emerging as a powerful tool in basic, translational and clinical research. In …

The mechanism and therapy of aortic aneurysms

J Gao, H Cao, G Hu, Y Wu, Y Xu, H Cui, HS Lu… - Signal transduction and …, 2023 - nature.com
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …

Transforming growth factor-β in stem cells and tissue homeostasis

X Xu, L Zheng, Q Yuan, G Zhen, JL Crane, X Zhou… - Bone research, 2018 - nature.com
Abstract TGF-β 1–3 are unique multi-functional growth factors that are only expressed in
mammals, and mainly secreted and stored as a latent complex in the extracellular matrix …

Biomedical simulations of nanoparticles drug delivery to blood hemodynamics in diseased organs: Synovitis problem

KS Mekheimer, RE Abo-Elkhair, SI Abdelsalam… - … Communications in Heat …, 2022 - Elsevier
Purpose Synovial fluid is an ultra-viscous plasma filtration that lubricates joint movement.
During acute accidents or a cartilage repair surgical intervention, blood is introduced into the …

Endothelial permeability, LDL deposition, and cardiovascular risk factors—A review

S Mundi, M Massaro, E Scoditti… - Cardiovascular …, 2018 - academic.oup.com
Early atherosclerosis features functional and structural changes in the endothelial barrier
function that affect the traffic of molecules and solutes between the vessel lumen and the …