Listeria monocytogenes, a model in infection biology

M Lecuit - Cellular microbiology, 2020 - Wiley Online Library
Listeria monocytogenes causes listeriosis, a systemic infection which manifests as
bacteremia, often complicated by meningoencephalitis in immunocompromised individuals …

Crossing the intestinal barrier via Listeria adhesion protein and internalin A

R Drolia, AK Bhunia - Trends in microbiology, 2019 - cell.com
The intestinal epithelial cell lining provides the first line of defense, yet foodborne pathogens
such as Listeria monocytogenes can overcome this barrier; however, the underlying …

[HTML][HTML] Geographic differences in gut microbiota composition impact susceptibility to enteric infection

AM Porras, Q Shi, H Zhou, R Callahan… - Cell Reports, 2021 - cell.com
Large-scale studies of human gut microbiomes have revealed broad differences in
composition across geographically distinct populations. Yet, studies examining impacts of …

[HTML][HTML] Different Shades of Listeria monocytogenes: Strain, Serotype, and Lineage-Based Variability in Virulence and Stress Tolerance Profiles

F Muchaamba, AK Eshwar, MJA Stevens… - Frontiers in …, 2022 - frontiersin.org
Listeria monocytogenes is a public health and food safety challenge due to its virulence and
natural stress resistance phenotypes. The variable distribution of L. monocytogenes …

[HTML][HTML] Listeria monocytogenes faecal carriage is common and depends on the gut microbiota

L Hafner, M Pichon, C Burucoa, SHA Nusser… - Nature …, 2021 - nature.com
Listeria genus comprises two pathogenic species, L. monocytogenes (Lm) and L. ivanovii,
and non-pathogenic species. All can thrive as saprophytes, whereas only pathogenic …

Listeria monocytogenes: review of pathogenesis and virulence determinants-targeted immunological assays

L Lopes-Luz, M Mendonça… - Critical Reviews in …, 2021 - Taylor & Francis
Listeria monocytogenes is one of the most invasive foodborne pathogens and is responsible
for numerous outbreaks worldwide. Most of the methods to detect this bacterium in food …

[HTML][HTML] Chromosomal barcodes for simultaneous tracking of near-isogenic bacterial strains in plant microbiota

J Ordon, J Thouin, RT Nakano, KW Ma, P Zhang… - Nature …, 2024 - nature.com
DNA-amplicon-based microbiota profiling can estimate species diversity and abundance but
cannot resolve genetic differences within individuals of the same species. Here we report …

Innate immune responses yield tissue-specific bottlenecks that scale with pathogen dose

K Hullahalli, KG Dailey… - Proceedings of the …, 2023 - National Acad Sciences
To cause infection, pathogens must overcome bottlenecks imposed by the host immune
system. These bottlenecks restrict the inoculum and largely determine whether pathogen …

Gastric acid and escape to systemic circulation represent major bottlenecks to host infection by Citrobacter rodentium

SE Woodward, SL Vogt, J Peña-Díaz… - The ISME …, 2023 - academic.oup.com
The gastrointestinal (GI) environment plays a critical role in shaping enteric infections. Host
environmental factors create bottlenecks, restrictive events that reduce the genetic diversity …

[HTML][HTML] Systemic infection facilitates transmission of Pseudomonas aeruginosa in mice

KER Bachta, JP Allen, BH Cheung, CH Chiu… - Nature …, 2020 - nature.com
Health care-associated infections such as Pseudomonas aeruginosa bacteremia pose a
major clinical risk for hospitalized patients. However, these systemic infections are …