Physical stability and dissolution behaviors of amorphous pharmaceutical solids: Role of surface and interface effects
Q Shi, SM Moinuddin, Y Wang, F Ahsan, F Li - International Journal of …, 2022 - Elsevier
Amorphous pharmaceutical solids (APS) are single-or multi-component systems in which
drugs exist in high-energy states with long-range disordered molecular packing. APSs have …
drugs exist in high-energy states with long-range disordered molecular packing. APSs have …
Recent advances in enhancement of dissolution and supersaturation of poorly water-soluble drug in amorphous pharmaceutical solids: A review
Q Shi, F Li, S Yeh, SM Moinuddin, J Xin, J Xu… - Aaps Pharmscitech, 2022 - Springer
Amorphization is one of the most effective pharmaceutical approaches to enhance the
dissolution and oral bioavailability of poorly water-soluble drugs. In recent years, amorphous …
dissolution and oral bioavailability of poorly water-soluble drugs. In recent years, amorphous …
Study of disordered mesoporous silica regarding intrinsic compound affinity to the carrier and drug-accessible surface area
A Niederquell, B Vraníková, M Kuentz - Molecular Pharmaceutics, 2023 - ACS Publications
There is increasing research interest in using mesoporous silica for the delivery of poorly
water-soluble drugs that are stabilized in a noncrystalline form. Most research has been …
water-soluble drugs that are stabilized in a noncrystalline form. Most research has been …
Characterization of drugs with good glass formers in loaded-mesoporous silica and its theoretical value relevance with mesopores surface and pore-filling capacity
The incorporation of a drug into mesoporous silica (MPS) is a promising strategy to stabilize
its amorphous form. However, the drug within MPS has shown incomplete release, despite a …
its amorphous form. However, the drug within MPS has shown incomplete release, despite a …
A comparative study of the pharmaceutical properties between amorphous drugs loaded-mesoporous silica and pure amorphous drugs prepared by solvent …
The formulation of poorly water-soluble drugs is one of the main challenges in the
pharmaceutical industry, especially in the development of oral dosage forms. Meanwhile …
pharmaceutical industry, especially in the development of oral dosage forms. Meanwhile …
Light-responsive mesoporous silica nanoparticles loaded with osmanthus fragrance for improving leather odor
X Hu, M Liu, Y Cheng, J Hu - ACS Applied Nano Materials, 2022 - ACS Publications
Improving the odor quality of leather is of great significance for leather commodities.
However, effectively and mildly released odor on targeted leather is still challenging in the …
However, effectively and mildly released odor on targeted leather is still challenging in the …
A Commentary on Co-Processed API as a Promising Approach to Improve Sustainability for the Pharmaceutical Industry
Pharmaceutical products represent a meaningful target for sustainability improvement and
emissions reduction. It is proposed here that rethinking the standard, and often linear …
emissions reduction. It is proposed here that rethinking the standard, and often linear …
Mesoporous Drug Delivery System: From Physical Properties of Drug in Solid State to Controlled Release
Y Wang, F Li, J Xin, J Xu, G Yu, Q Shi - Molecules, 2023 - mdpi.com
Mesoporous materials, which exhibit great potential in the control of polymorphs and
delivery of poorly water-soluble drugs, have obtained considerable attention in the field of …
delivery of poorly water-soluble drugs, have obtained considerable attention in the field of …
Studying the Intermolecular Interactions, Structural Dynamics, and Non-Equilibrium Kinetics of Cilnidipine Infiltrated into Alumina and Silica Pores
In the present study, the behavior of the calcium channel blocker cilnidipine (CLN) infiltrated
into silica (SiO2) and anodic aluminum oxide (AAO) porous membranes characterized by a …
into silica (SiO2) and anodic aluminum oxide (AAO) porous membranes characterized by a …
Practical Aspects of XPS: From Sample Preparation to Spectra Interpretation
DY Zemlyanov - Applications of X-ray Photoelectron Spectroscopy …, 2023 - World Scientific
Nowadays, X-ray photoelectron spectroscopy (XPS) is one of the most widely used surface
characterization techniques in materials science and chemistry, spreading to pharmacy …
characterization techniques in materials science and chemistry, spreading to pharmacy …