Synthesis of Chiral Tetrasubstituted Azetidines from Donor–Acceptor Azetines via Asymmetric Copper (I)‐Catalyzed Imido‐Ylide [3+ 1]‐Cycloaddition with Metallo …

KO Marichev, K Wang, K Dong, N Greco… - Angewandte Chemie …, 2019 - Wiley Online Library
The all‐cis stereoisomers of tetrasubstituted azetidine‐2‐carboxylic acids and derivatives
that possess three chiral centers have been prepared in high yield and stereocontrol from …

Chiral donor–acceptor azetines as powerful reactants for synthesis of amino acid derivatives

KO Marichev, K Dong, LA Massey, Y Deng… - Nature …, 2019 - nature.com
Coupling reactions of amines and alcohols are of central importance for applications in
chemistry and biology. These transformations typically involve the use of a reagent …

Copper (I)-catalyzed highly enantioselective [3+ 3]-cycloaddition of γ-alkyl enoldiazoacetates with nitrones

K Dong, X Xu, MP Doyle - Organic Chemistry Frontiers, 2020 - pubs.rsc.org
Chiral copper (I) catalysts are preferred over chiral dirhodium (II) catalysts for [3+ 3]-
cycloaddition reactions of γ-alkyl-substituted enoldiazoacetates compounds with nitrones …

Role of Donor–Acceptor Cyclopropenes in Metal Carbene Reactions. Conversion of E-Substituted Enoldiazoacetates to Z-Substituted Metallo-Enolcarbenes

K Dong, KO Marichev, MP Doyle - Organometallics, 2019 - ACS Publications
The influence of geometrical isomers of silyl-protected γ-substituted enoldiazoacetates has
been examined in transition-metal-catalyzed vinylcarbene cycloaddition reactions. These …

Reactions of Aldehydes and Ketones and their Derivatives

BA Murray - Organic Reaction Mechanisms 2011: An annual …, 2014 - Wiley Online Library
Carbohydrate‐based benzylidene acetals undergo reductive ring opening. 1‐β‐O‐Acyl
glucoside conjugates of phenylacetic acids have been synthesized, and their acyl migration …

Challenges in the Highly Selective [3 + 1]-Cycloaddition of an Enoldiazoacetamide to Form a Donor–Acceptor Cis-Cyclobutenecarboxamide

S Joyasawal, D Ma, MP Doyle - Molecules, 2021 - mdpi.com
A substituted donor–acceptor cyclobutenecarboxamide is synthesized with modest
enantiocontrol through a chiral copper (I) complex catalyzed [3+ 1]-cycloaddition reaction of …

Addition Reactions: Cycloaddition

N Dennis - Organic Reaction Mechanisms· 2016: An annual …, 2020 - Wiley Online Library
Summary This Chapter Contains Sections titled: 2+ 2‐Cycloaddition 2+ 3‐Cycloaddition 2+
4‐Cycloaddition Miscellaneous References Tetrafluorothiophene S, S‐dioxide is a potent …

An Extraordinary Journey with Tert-butyl Nitrite and Diazo Compounds: from Nitrile Oxides to N-heterocycles

L De Angelis - 2022 - search.proquest.com
Terminal diazo compounds undergo smooth nitrosyl exchange with TBN to furnish nitrile
oxides in situ after the loss of molecular nitrogen. Nitrile oxides are very useful reactive …

Carbenes and Nitrenes

E Gras, S Chassaing - … 2019: An annual survey covering the …, 2023 - Wiley Online Library
A general review has appeared on catalyst design assisted by computations featuring some
examples of carbenes acting either as organocatalysts or in situ generated reagents in metal …

[引用][C] (3+ 1)-and (3+ 3)-Cycloadditions

KO Marichev, MP Doyle - 2022 - Elsevier