The neurodevelopmental and dopamine hypotheses are leading theories of the
pathoetiology of schizophrenia, but they were developed in isolation. However, since they …

The transition from adolescence to adulthood is characterized by improvements in higher-
order cognitive abilities and corresponding refinements of the structure and function of the …

Autism is a complex neurodevelopmental condition, and little is known about its
neurobiology. Much of autism research has focused on the social, communication and …

Throughout development, the brain transits from early highly synchronous activity patterns to
a mature state with sparse and decorrelated neural activity, yet the mechanisms underlying …

Deep learning has seen remarkable developments over the last years, many of them
inspired by neuroscience. However, the main learning mechanism behind these advances …

Oxytocin is important for social interactions and maternal behaviour. However, little is known
about when, where and how oxytocin modulates neural circuits to improve social cognition …

Recent years have seen a growing interest in inhibitory interneurons and their circuits. A
striking property of cortical inhibition is how tightly it balances excitation. Inhibitory currents …

Synapses are highly plastic and are modified by changes in patterns of neural activity or
sensory experience. Plasticity of cortical excitatory synapses is thought to be important for …

Oxytocin is a neuropeptide important for social behaviors such as maternal care and parent–
infant bonding. It is believed that oxytocin receptor signaling in the brain is critical for these …

Animal and human postmortem studies provide evidence for changes in gamma-
aminobutyric acid (GABA) and glutamate in prefrontal cortex (PFC) during adolescence …