Failed tubule recovery, AKI-CKD transition, and kidney disease progression

MA Venkatachalam, JM Weinberg, W Kriz… - Journal of the …, 2015 - journals.lww.com
The transition of AKI to CKD has major clinical significance. As reviewed here, recent studies
show that a subpopulation of dedifferentiated, proliferating tubules recovering from AKI …

Acute kidney injury: a springboard for progression in chronic kidney disease

MA Venkatachalam, KA Griffin, R Lan… - American Journal …, 2010 - journals.physiology.org
Recently published epidemiological and outcome analysis studies have brought to our
attention the important role played by acute kidney injury (AKI) in the progression of chronic …

Long-term kidney function recovery and mortality after COVID-19-associated acute kidney injury: an international multi-centre observational cohort study

BWL Tan, BWQ Tan, ALM Tan, ER Schriver… - …, 2023 - thelancet.com
Background While acute kidney injury (AKI) is a common complication in COVID-19, data on
post-AKI kidney function recovery and the clinical factors associated with poor kidney …

Molecular mechanisms of the acute kidney injury to chronic kidney disease transition: an updated view

F Guzzi, L Cirillo, RM Roperto, P Romagnani… - International journal of …, 2019 - mdpi.com
Increasing evidence has demonstrated the bidirectional link between acute kidney injury
(AKI) and chronic kidney disease (CKD) such that, in the clinical setting, the new concept of …

Long-term prognosis after acute kidney injury (AKI): what is the role of baseline kidney function and recovery? A systematic review

S Sawhney, M Mitchell, A Marks, N Fluck, C Black - BMJ open, 2015 - bmjopen.bmj.com
Objectives To summarise the evidence from studies of acute kidney injury (AKI) with regard
to the effect of pre-AKI renal function and post-AKI renal function recovery on long-term …

Acute kidney injury in elderly persons

SG Coca - American Journal of Kidney Diseases, 2010 - Elsevier
The incidence rate of acute kidney injury (AKI) is highest in elderly patients, who make up an
ever-growing segment of the population at large. AKI in these patients is associated with an …

The aftermath of acute kidney injury: a narrative review of long-term mortality and renal function

G Fortrie, HRH de Geus, MGH Betjes - Critical Care, 2019 - Springer
Acute kidney injury (AKI) is a frequent complication of hospitalization and is associated with
an increased risk of chronic kidney disease (CKD), end-stage renal disease (ESRD), and …

AKI transition of care: a potential opportunity to detect and prevent CKD

SL Goldstein, BL Jaber, S Faubel… - Clinical Journal of the …, 2013 - journals.lww.com
The incidence rate of AKI is increasing across the spectrum of hospitalized children and
adults. Given the increased morbidity and mortality associated with AKI, significant research …

Recommendations for the management of crush victims in mass disasters

MS Sever, R Vanholder, I Ashkenazi… - Nephrology dialysis …, 2012 - biblio.ugent.be
" Recommendations for the management of crush victims in mass disasters" aims to assist
medics, paramedics and rescue team members who provide care during disasters …

GPR120/FFAR4 pharmacology: focus on agonists in type 2 diabetes mellitus drug discovery

G Carullo, S Mazzotta, M Vega-Holm… - Journal of Medicinal …, 2021 - ACS Publications
The G-protein coupled receptors (GPCRs) activated by free fatty acids (FFAs) have emerged
as new and exciting drug targets, due to their plausible translation from pharmacology to …