Developmental small RNA transcriptomics reveals divergent evolution of the conserved microRNA miR-100 and the let-7-complex in nematodes

DR Sharma, W Röseler, H Witte, MS Werner… - bioRxiv, 2024 - biorxiv.org
Small RNAs have emerged as one of the key post-transcriptional regulators and can be
broadly categorised into microRNAs (miRNAs), small-interfering RNAs (siRNAs), and PIWI …

Characterization of the Pristionchus pacificus “epigenetic toolkit” reveals the evolutionary loss of the histone methyltransferase complex PRC2

AL Brown, AB Meiborg, M Franz-Wachtel, B Macek… - Genetics, 2024 - academic.oup.com
Comparative approaches have revealed both divergent and convergent paths to achieving
shared developmental outcomes. Thus, only through assembling multiple case studies can …

Starvation resistance in the nematode Pristionchus pacificus requires a conserved supplementary nuclear receptor

T Theska, T Renahan, RJ Sommer - Zoological Letters, 2024 - Springer
Nuclear hormone receptors (NHRs) are a deeply-conserved superfamily of metazoan
transcription factors, which fine-tune the expression of their regulatory target genes in …

Microbiota succession influences nematode physiology in a beetle microcosm ecosystem

WS Lo, RJ Sommer, Z Han - Nature Communications, 2024 - nature.com
Unravelling the multifaceted and bidirectional interactions between microbiota and host
physiology represents a major scientific challenge. Here, we utilise the nematode model …

The genome assembly of Rhabditoides inermis from a complex microbial community reveals further evidence for parallel gene family expansions across multiple …

C Roedelsperger, W Röseler, M Athanasouli… - bioRxiv, 2024 - biorxiv.org
Free-living nematodes such as Caenorhabditis elegans and Pristionchus pacificus are
powerful model systems for linking specific traits to their underlying genetic basis. To trace …