Proteases enzymatically hydrolyze peptide bonds in substrate proteins, resulting in a
widespread, irreversible posttranslational modification of the protein's structure and …

Proteolytic processing is a ubiquitous and irreversible post-translational modification
involving limited and highly specific hydrolysis of peptide and isopeptide bonds of a protein …

Accurate quantification of protein expression in biological systems is an increasingly
important part of proteomics research. Incorporation of differential stable isotopes in samples …

A myriad of co-and post-translational modifications occur at protein N-and C-termini,
resulting in an extra layer of proteome complexity and an additional source of protein …

Most proteins in all organisms undergo crucial N‐terminal modifications involving N‐
terminal methionine excision, N‐α‐acetylation or N‐myristoylation (N‐Myr), or S …

The identification of biocompatible nanomaterials with high conductivities as sensing
interfaces is important in developing novel electrochemical cytosensors. We prepared a …

Various forms of protein (proteoforms) are generated by genetic variations, alternative
splicing, alternative translation initiation, co-or post-translational modification and …

N-terminomics is a rapidly evolving branch of proteomics that encompasses the study of
protein N-terminal sequence. A proteome-wide collection of such sequences has been …

The analysis of protein N-termini is of great importance for understanding the protein
function and elucidating the proteolytic processing. Herein, we develop a negative …

Proteogenomics consists of the annotation or reannotation of protein‐coding nucleic acid
sequences based on the empirical observation of their gene products. While functional …