Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors with high prevalence
among adult populations and elevated costs for public health systems worldwide. Despite …

Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including type 2 diabetes, cardiovascular diseases, nonalcoholic fatty liver disease and …

Adipose tissue constitutes an extremely active endocrine organ with a network of signaling
pathways enabling the organism to adapt to a wide range of different metabolic challenges …

In adipocytes the hydrolysis of TAG to produce fatty acids and glycerol under fasting
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …

The origin of brown adipocytes arising in white adipose tissue (WAT) after cold
acclimatization is unclear. Here, we demonstrate that several UCP1-immunoreactive brown …

Brown adipocytes dissipate energy, whereas white adipocytes are an energy storage site.
We explored the plasticity of different white adipose tissue depots in acquiring a brown …

Insulin resistance is a major metabolic feature of obesity and is a key factor in the etiology of
a number of diseases, including type 2 diabetes. In this review, we discuss potential …

The aim of the present work was to study whether the leptin-adiponectin axis may have a
pathophysiological role in the increased systemic inflammation and oxidative stress …

Obesity, the most common nutritional disorder in industrialized countries, is associated with
an increased mortality and morbidity of cardiovascular disease (CVD). Obesity is primarily …

Fatty acid binding protein 4 (FABP4, also known as aP2) is a cytoplasmic fatty acid
chaperone expressed primarily in adipocytes and myeloid cells and implicated in the …