Animal studies have been instrumental in providing knowledge about the molecular and
neural mechanisms underlying drug addiction. Recently, the fruit fly Drosophila …

Drosophila melanogaster has become a significant model organism for alcohol research. In
flies, a rich variety of behaviors can be leveraged for identifying genes affecting alcohol …

Background Despite the profound clinical significance and strong heritability of alcohol use
disorder (AUD), we do not yet have a comprehensive understanding of the naturally …

Adverse, unfavourable life conditions, particularly during early life stages and infancy, can
lead to epigenetic regulation of genes involved in stress-response, behavioral disinhibition …

Sustained or repeated exposure to sedating drugs, such as alcohol, triggers homeostatic
adaptations in the brain that lead to the development of drug tolerance and dependence …

Cues associated with intoxication can elicit cravings for alcohol, leading to increased
consumption and relapse in people recovering from alcohol use disorder. Petruccelli et al …

Alcohol withdrawal seizures are part of the symptomatology of severe alcohol dependence
and are believed to originate from long‐term neural adaptations that counter the central …

A growing body of evidence has shown that alcohol alters the activity of the innate immune
system and that changes in innate immune system activity can influence alcohol‐related …

Ethanol consumption has been shown to have many deleterious effects, including
behavioral alterations, motor deficits, reduction in inhibition, and alteration of neurochemical …

Drug addiction is a complex condition of compulsive drug use that results in devastating
physical and social consequences. Drosophila melanogaster has recently emerged as a …