Radiation effects on brain extracellular matrix

EV Grigorieva - Frontiers in Oncology, 2020 - frontiersin.org
Radiotherapy is an important therapeutic approach to treating malignant tumors of different
localization, including brain cancer. Glioblastoma multiforme (GBM) represents the most …

[HTML][HTML] Enhancement radiation-induced apoptosis in C6 glioma tumor-bearing rats via pH-responsive magnetic graphene oxide nanocarrier

S Shirvalilou, S Khoei, S Khoee, SR Mahdavi… - … of Photochemistry and …, 2020 - Elsevier
iodo-2-deoxyuridine (IUdR) has been demonstrated to induce an appreciable
radiosensitizing effect on glioblastoma patients, but due to the short circulation half-life times …

Risk factors for radiation necrosis in patients undergoing cranial stereotactic radiosurgery

J Kerschbaumer, M Demetz, A Krigers… - Cancers, 2021 - mdpi.com
Simple Summary Radiation necrosis is a known complication after stereotactic radiosurgery
of intracranial tumors. We evaluated 388 patients who underwent stereotactic radiosurgery …

Determinants of cerebral radionecrosis in animal models: A systematic review

S Al-Rubaiey, C Senger, J Bukatz, K Krantchev… - Radiotherapy and …, 2024 - Elsevier
Background Radionecrosis is a common complication in radiation oncology, while
mechanisms and risk factors have yet to be fully explored. We therefore conducted a …

Neuroprotective effect of resveratrol against radiation after surgically induced brain injury by reducing oxidative stress, inflammation, and apoptosis through NRf2/HO …

Y Zhang, X Zhu, J Zhao, X Gao… - Journal of Biochemical …, 2020 - Wiley Online Library
The impact of resveratrol (RSV) on radiation (RAD)‐induced brain injury in rats' brains was
investigated. A total of 40 male Wistar Albino rats were randomly divided into four groups …

Presence of activated (phosphorylated) STAT3 in radiation necrosis following stereotactic radiosurgery for brain metastases

PA Jablonska, N Galán, J Barranco, S Leon… - International Journal of …, 2023 - mdpi.com
Brain radiation necrosis (RN) is a subacute or late adverse event following radiotherapy,
involving an exacerbated inflammatory response of the brain tissue. The risk of symptomatic …

Psoralen as a Photosensitizers for Photodynamic Therapy by Means of In Vitro Cherenkov Light

L Hübinger, R Runge, T Rosenberg… - International Journal of …, 2022 - mdpi.com
Possible enhancements of DNA damage with light of different wavelengths and ionizing
radiation (Rhenium-188—a high energy beta emitter (Re-188)) on plasmid DNA and FaDu …

Chronic pathophysiological changes in the normal brain parenchyma caused by radiotherapy accelerate glioma progression

Y Tsuji, N Nonoguchi, D Okuzaki, Y Wada… - Scientific Reports, 2021 - nature.com
Radiation therapy is one of standard treatment for malignant glioma after surgery. The
microenvironment after irradiation is considered not to be suitable for the survival of tumor …

Investigation of Photodynamic Therapy Promoted by Cherenkov Light Activated Photosensitizers—New Aspects and Revelations

L Hübinger, K Wetzig, R Runge, H Hartmann, F Tillner… - Pharmaceutics, 2024 - mdpi.com
This work investigates the proposed enhanced efficacy of photodynamic therapy (PDT) by
activating photosensitizers (PSs) with Cherenkov light (CL). The approaches of Yoon et al. to …

Evolution of radiation-induced temporal lobe injury after intensity-modulated radiation therapy in nasopharyngeal carcinoma: a large cohort retrospective study

J Hou, Y He, H Li, Z Ai, Q Lu, B Zeng, C Xie, X Yu - Radiation Oncology, 2024 - Springer
Background Previous studies have demonstrated conflicting findings regarding the initial
MRI patterns of radiotherapy-induced temporal lobe injury (RTLI) and the evolution of …