Ovarian aging refers to the process by which ovarian function declines until eventual failure.
The pathogenesis of ovarian aging is complex and diverse; oxidative stress (OS) is …

Almost fifty years after its first introduction into clinical care, clozapine remains the only
evidence-based pharmacological option for treatment-resistant schizophrenia (TRS), which …

Abstract Background Glioblastoma (GBM; grade IV glioma) is characterized by a very short
overall survival time and extremely low 5-year survival rates. We intend to promote …

Age-related decline in female fertility is a common feature that occurs in the fourth decade of
women as a result of a reduction in both oocyte quality and quantity [1]. However, strategies …

Risperidone is one of the most commonly used antipsychotics (AP), due to its safety and
efficacy in reducing psychotic symptoms. Despite the favorable side effect profile, the …

Over the last few decades, using natural products has been increased to treat different
diseases. Today, great attention has been pointed toward the usage of natural products …

Numerous studies have established that the hypoxic conditions within ovarian follicles
induce apoptosis in granulosa cells (GCs), a pivotal hallmark of follicular atresia. Melatonin …

Abstract Granulosa Cells (GCs) are sensitive to excessive production of reactive oxygen
species (ROS). Quercetin (QUR) is a free radical scavenger which can alleviate oxidative …

Sarcodon imbricatus, a rare medicinal and edible fungus, has various pharmacological
bioactivities. The present study systematically investigated the protective effects of S …

In mammalian ovaries, the avascular environment within follicular cavity is supposed to
cause hypoxic status in granulosa cells (GCs), leading to apoptotic cell death accompanied …