Disordered proteins have long been known to help mediate tolerance to different abiotic
stresses including freezing, osmotic stress, high temperatures, and desiccation in a diverse …

The extent of the effect of cellular crowding and cosolutes on the functioning of proteins and
cells is manifold and includes the stabilization of the biomolecular systems, the excluded …

Limited fractionation of yellow pea yielded functional protein fractions with higher gelling
capacity. Pea protein concentrates were obtained by dispersing flour at unadjusted pH …

The stabilizing effect of sugar-glass matrix materials for freeze-drying proteins or nucleic
acids has been variously ascribed to the thermodynamic effect of 'water replacement'by …

An improved parameter set for explicit-solvent simulations of carbohydrates (referred to as
GROMOS 53A6GLYC) is presented, allowing proper description of the most stable …

In order to investigate the cryoprotective mechanism of trehalose on proteins, we use
molecular dynamics computer simulations to study the microscopic dynamics of water upon …

Many proteins, especially those used as therapeutics, are unstable to storage and shipping
temperatures, leading to increased costs in research and industry. Therefore, the design and …

Legumes such as pea and soy have the ability to form coacervates in solution, which
depends on the pH and salt concentration. We studied the phenomenon of coacervation for …

Water structure in aqueous osmolyte solutions, deduced from the slight alteration in the
water–water radial distribution function, the decrease in water–water hydrogen bonding, and …

The remarkable adaptive strategies of insects to extreme environments are linked to the
biochemical compounds in their body fluids. Trehalose, a versatile sugar molecule, can …