Many psychiatric disorders, despite their specific characteristics, share deficits in the
cognitive domain including executive functions, emotional control and memory. However …

Environmental enrichment (EE) has been shown to have powerful beneficial effects on a
variety of physiological and pathological processes. Accumulating evidence indicates that …

Environmental enrichment (EE) was shown recently to accelerate brain development in
rodents. Increased levels of maternal care, and particularly tactile stimulation through licking …

Human amyloid precursor protein (hAPP) transgenic mice with high levels of amyloid-β (Aβ)
develop behavioral deficits that correlate with the depletion of synaptic activity-related …

Lifelong cognitive stimulation is associated with a lower risk of Alzheimer's disease (AD), but
causality is difficult to prove. We therefore sought to investigate the preventative potential of …

Prevailing views of neurotrophin action hold that the transcription factor CREB is
constitutively bound to target genes with transcriptional activation occurring via CREB …

Tinnitus is proposed to be caused by decreased central input from the cochlea, followed by
increased spontaneous and evoked subcortical activity that is interpreted as compensation …

Exposure to an enriched environment (EE), consisting of a combination of increased
exercise, social interactions and learning, has been shown to produce many positive effects …

Drugs of abuse and many other kinds of experiences share the ability to alter the
morphology of neuronal dendrites and spines, the primary site of excitatory synapses in the …

A crucial issue in neurobiology is to understand the main mechanisms restricting neural
plasticity to brief windows of early postnatal life. The visual system is one of the paradigmatic …