Intratumor heterogeneity is the main obstacle to effective cancer treatment and personalized
medicine. Both genetic and epigenetic sources of intratumor heterogeneity are well …

Brain tumors are a widespread and serious neurological phenomenon that can be life-
threatening. The computing field has allowed for the development of artificial intelligence …

Immunotherapy strategies have been emerging as powerful weapons against cancer. Early
clinical trials reveal that overall response to immunotherapy is low in breast cancer patients …

In-depth insights in cancer biology over the past decades have highlighted the important
roles of epigenetic mechanisms in the initiation and progression of tumorigenesis. The …

Recent discoveries have led to the development of novel ideas and techniques that have
helped elucidate the correlation between epigenetics and tumor biology. Nowadays, the …

Accumulating evidence has indicated the importance of microRNAs (miRs) in the biology of
human malignancies by targeting multiple signaling pathways and different Messenger RNA …

Background. Hopes to identify genetic susceptibility loci accounting for the heritability seen
in unipolar depression have not been fully realized. Family history remains the 'gold …

It has been reported that the expression of angiomotin (AMOT) is upregulated in breast
cancer. However, the regulatory mechanism remains unknown. In the present study, we …

Background Aerobic glycolysis, also known as the Warburg effect, is predominantly
upregulated in a variety of solid tumors, including breast cancer. We have previously …

The miR-29 family comprises miR-29a, miR-29b, and miR-29c, and these molecules play
crucial and partially overlapped functions in solid tumors, in which the different isoforms are …