The human upper respiratory tract (URT) offers a variety of niches for microbial colonization.
Local microbial communities are shaped by the different characteristics of the specific …

Streptococcus pneumoniae has a complex relationship with its obligate human host. On the
one hand, the pneumococci are highly adapted commensals, and their main reservoir on the …

Asthma is a common chronic respiratory disease affecting more than 300 million people
worldwide. Clinical features of asthma and its immunological and molecular etiology vary …

Worldwide 300 million children and adults are affected by asthma. The development of
asthma is influenced by environmental and other exogenous factors synergizing with …

Asthma is a complex disease that often starts in childhood. Genomic and environmental
factors as well as aberrant immune maturation early in life can contribute to the onset of …

The intestinal microbiota has been implicated in insulin resistance, although evidence
regarding causality in humans is scarce. We therefore studied the effect of lean donor …

The respiratory tract is a complex organ system that is responsible for the exchange of
oxygen and carbon dioxide. The human respiratory tract spans from the nostrils to the lung …

In this Review, I present evidence supporting a multifactorial causation of childhood acute
lymphoblastic leukaemia (ALL), a major subtype of paediatric cancer. ALL evolves in two …

Human body is inhabited by vast number of microorganisms which form a complex
ecological community and influence the human physiology, in the aspect of both health and …

The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …