[HTML][HTML] microRNAs biogenesis, functions and role in tumor angiogenesis
T Annese, R Tamma, M De Giorgis, D Ribatti - Frontiers in oncology, 2020 - frontiersin.org
microRNAs (miRNAs) are small non-coding RNA molecules, evolutionary conserved. They
target more than one mRNAs, thus influencing multiple molecular pathways, but also …
target more than one mRNAs, thus influencing multiple molecular pathways, but also …
[HTML][HTML] Overview of microRNA biology
In considering an overview of microRNA biology, it is useful to consider microRNAs as a part
of cellular communication. At the simplest level, microRNAs act to decrease the expression …
of cellular communication. At the simplest level, microRNAs act to decrease the expression …
[HTML][HTML] circRNA biogenesis competes with pre-mRNA splicing
R Ashwal-Fluss, M Meyer, NR Pamudurti, A Ivanov… - Molecular cell, 2014 - cell.com
Circular RNAs (circRNAs) are widely expressed noncoding RNAs. However, their
biogenesis and possible functions are poorly understood. Here, by studying circRNAs that …
biogenesis and possible functions are poorly understood. Here, by studying circRNAs that …
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells
F Peng, J Xu, B Cui, Q Liang, S Zeng, B He, H Zou, M Li… - Cell research, 2021 - nature.com
RNase III DROSHA is upregulated in multiple cancers and contributes to tumor progression
by hitherto unclear mechanisms. Here, we demonstrate that DROSHA interacts with β …
by hitherto unclear mechanisms. Here, we demonstrate that DROSHA interacts with β …
Interplay between miRNAs and host genes and their role in cancer
MicroRNAs (miRNAs) are small endogenous non-coding functional RNAs that post-
transcriptionally regulate gene expression. They play essential roles in nearly all biological …
transcriptionally regulate gene expression. They play essential roles in nearly all biological …
microRNAs are biomarkers of oncogenic human papillomavirus infections
X Wang, HK Wang, Y Li, M Hafner… - Proceedings of the …, 2014 - National Acad Sciences
Cellular and viral microRNAs (miRNAs) are the transcriptional products of RNA polymerase
II and are regulated by transcriptional factors for their differential expression. The altered …
II and are regulated by transcriptional factors for their differential expression. The altered …
[HTML][HTML] Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms
H Ishii, M Saitoh, K Sakamoto, T Kondo, R Katoh… - Journal of Biological …, 2014 - ASBMB
ESRP1 (epithelial splicing regulatory protein 1) and ESRP2 regulate alternative splicing
events associated with epithelial phenotypes of cells, and both are down-regulated during …
events associated with epithelial phenotypes of cells, and both are down-regulated during …
MicroRNA in teleost fish
TT Bizuayehu, I Babiak - Genome biology and evolution, 2014 - academic.oup.com
MicroRNAs (miRNAs) are transcriptional and posttranscriptional regulators involved in
nearly all known biological processes in distant eukaryotic clades. Their discovery and …
nearly all known biological processes in distant eukaryotic clades. Their discovery and …
Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure
Dysfunction of microRNA (miRNA) metabolism is thought to underlie diseases affecting
motoneurons. One miRNA, miR-218, is abundantly and selectively expressed by developing …
motoneurons. One miRNA, miR-218, is abundantly and selectively expressed by developing …
A two-way street: regulatory interplay between RNA polymerase and nascent RNA structure
J Zhang, R Landick - Trends in biochemical sciences, 2016 - cell.com
The vectorial (5′-to-3′ at varying velocity) synthesis of RNA by cellular RNA polymerases
(RNAPs) creates a rugged kinetic landscape, demarcated by frequent, sometimes long …
(RNAPs) creates a rugged kinetic landscape, demarcated by frequent, sometimes long …