[HTML][HTML] Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup

A Zarbock, MK Nadim, P Pickkers, H Gomez… - Nature Reviews …, 2023 - nature.com
Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and is
strongly associated with adverse outcomes, including an increased risk of chronic kidney …

[HTML][HTML] Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment

S Peerapornratana, CL Manrique-Caballero… - Kidney international, 2019 - Elsevier
Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

[HTML][HTML] SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

J Jansen, KC Reimer, JS Nagai, FS Varghese… - Cell stem cell, 2022 - cell.com
Kidney failure is frequently observed during and after COVID-19, but it remains elusive
whether this is a direct effect of the virus. Here, we report that SARS-CoV-2 directly infects …

Association of body mass index and age with morbidity and mortality in patients hospitalized with COVID-19: results from the American Heart Association COVID-19 …

NS Hendren, JA De Lemos, C Ayers, SR Das, A Rao… - Circulation, 2021 - Am Heart Assoc
Background: Obesity may contribute to adverse outcomes in coronavirus disease 2019
(COVID-19). However, studies of large, broadly generalizable patient populations are …

Kidney physiology and susceptibility to acute kidney injury: implications for renoprotection

H Scholz, FJ Boivin, KM Schmidt-Ott… - Nature Reviews …, 2021 - nature.com
Kidney damage varies according to the primary insult. Different aetiologies of acute kidney
injury (AKI), including kidney ischaemia, exposure to nephrotoxins, dehydration or sepsis …

[HTML][HTML] Targeting ferroptosis in acute kidney injury

L Ni, C Yuan, X Wu - Cell Death & Disease, 2022 - nature.com
Acute kidney injury (AKI) is a major public health problem with high incidence and mortality.
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …

Global epidemiology and outcomes of acute kidney injury

EAJ Hoste, JA Kellum, NM Selby, A Zarbock… - Nature Reviews …, 2018 - nature.com
Acute kidney injury (AKI) is a commonly encountered syndrome associated with various
aetiologies and pathophysiological processes leading to decreased kidney function. In …

[HTML][HTML] Timing of initiation of renal-replacement therapy in acute kidney injury.

SM Bagshaw, R Wald, NKJ Adhikari, R Bellomo… - The New England …, 2020 - sonar.ch
We conducted a multinational, randomized, controlled trial involving critically ill patients with
severe acute kidney injury. Patients were randomly assigned to receive an accelerated …

[HTML][HTML] The prevalence of acute kidney injury in patients hospitalized with COVID-19 infection: a systematic review and meta-analysis

SA Silver, W Beaubien-Souligny, PS Shah, S Harel… - Kidney medicine, 2021 - Elsevier
Rationale & Objective Coronavirus disease 2019 (COVID-19) may be associated with high
rates of acute kidney injury (AKI) and kidney replacement therapy (KRT), potentially …

Sepsis associated acute kidney injury

JT Poston, JL Koyner - Bmj, 2019 - bmj.com
Sepsis is defined as organ dysfunction resulting from the host's deleterious response to
infection. One of the most common organs affected is the kidneys, resulting in sepsis …