[HTML][HTML] SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy
The COVID-19 pandemic is an emerging threat to global public health. While our current
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …
Interaction of SARS-CoV-2 and other coronavirus with ACE (angiotensin-converting enzyme)-2 as their main receptor: therapeutic implications
AM Davidson, J Wysocki, D Batlle - Hypertension, 2020 - Am Heart Assoc
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 originated from Wuhan,
China, in December 2019 and rapidly spread to other areas worldwide. Since then …
China, in December 2019 and rapidly spread to other areas worldwide. Since then …
[HTML][HTML] COVID-19 and individual genetic susceptibility/receptivity: role of ACE1/ACE2 genes, immunity, inflammation and coagulation. Might the double X …
D Gemmati, B Bramanti, ML Serino… - International journal of …, 2020 - mdpi.com
In December 2019, a novel severe acute respiratory syndrome (SARS) from a new
coronavirus (SARS-CoV-2) was recognized in the city of Wuhan, China. Rapidly, it became …
coronavirus (SARS-CoV-2) was recognized in the city of Wuhan, China. Rapidly, it became …
[HTML][HTML] Animal models for COVID-19: advances, gaps and perspectives
C Fan, Y Wu, X Rui, Y Yang, C Ling, S Liu… - Signal transduction and …, 2022 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, is the most consequential pandemic of this
century. Since the outbreak in late 2019, animal models have been playing crucial roles in …
century. Since the outbreak in late 2019, animal models have been playing crucial roles in …
[HTML][HTML] Vitamin D alleviates lipopolysaccharide‑induced acute lung injury via regulation of the renin‑angiotensin system
J Xu, J Yang, J Chen, Q Luo… - Molecular …, 2017 - spandidos-publications.com
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are the clinical
manifestations of severe lung damage and respiratory failure. ALI and ARDS result are …
manifestations of severe lung damage and respiratory failure. ALI and ARDS result are …
[HTML][HTML] Oxidative stress and inflammation in COVID-19-associated sepsis: the potential role of anti-oxidant therapy in avoiding disease progression
J Beltrán-García, R Osca-Verdegal, FV Pallardó… - Antioxidants, 2020 - mdpi.com
Since the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak
emerged, countless efforts are being made worldwide to understand the molecular …
emerged, countless efforts are being made worldwide to understand the molecular …
[HTML][HTML] Quinolines-Based SARS-CoV-2 3CLpro and RdRp Inhibitors and Spike-RBD-ACE2 Inhibitor for Drug-Repurposing Against COVID-19: An in silico Analysis
The novel coronavirus SARS-CoV-2 disease “COVID-19” emerged in China and rapidly
spread to other countries; due to its rapid worldwide spread, the WHO has declared this as a …
spread to other countries; due to its rapid worldwide spread, the WHO has declared this as a …
Mechanisms of diabetic complications
It is increasingly apparent that not only is a cure for the current worldwide diabetes epidemic
required, but also for its major complications, affecting both small and large blood vessels …
required, but also for its major complications, affecting both small and large blood vessels …
[HTML][HTML] COVID-19 vasculopathy: mounting evidence for an indirect mechanism of endothelial injury
Patients with coronavirus disease 2019 (COVID-19) who are critically ill develop vascular
complications characterized by thrombosis of small, medium, and large vessels. Dysfunction …
complications characterized by thrombosis of small, medium, and large vessels. Dysfunction …
COVID-19 and cardiovascular consequences: Is the endothelial dysfunction the hardest challenge?
Abstract A Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) has become
a pandemic disease named Coronavirus Disease-19 (COVID-19) of epochal dimension …
a pandemic disease named Coronavirus Disease-19 (COVID-19) of epochal dimension …