Two principal theories for the pathogenesis of glaucomatous optic neuropathy (GON) have
been described—a mechanical and a vascular theory. Both have been defended by various …

The vasculature of the eye and the heart share several common characteristics. The easily
accessible vessels of the eye are therefore—to some extent—a window to the heart. There is …

OBJECTIVE: To assess the impact of vascular risk factors on the prevalence of primary open
angle glaucoma. DESIGN: Population-based cross-sectional study. PARTICIPANTS: Four …

Several mechanisms have been postulated to explain the optic nerve damage that occurs in
primary open angle glaucoma (POAG). No single mechanism can adequately explain the …

Vascular dysregulation refers to the regulation of blood flow that is not adapted to the needs
of the respective tissue. We distinguish primary vascular dysregulation (PVD, formerly called …

The regulation of ocular perfusion is different for different parts of the eye. Observations on
the retina can, therefore, not be extrapolated to the optic nerve head. Extraocular vessels …

Vasospasm can have many different causes and can occur in a variety of diseases,
including infectious, autoimmune, and ophthalmic diseases, as well as in otherwise healthy …

Glaucomatous optic neuropathy implies loss of neural tissue, activation of glial cells, tissue
remodeling, and change of blood flow. The blood flow reduction is not only secondary but …

Glaucoma can be defined as an optic nerve disease with typical morphological and
functional changes. There are many risk factors associated with this neuropathy. The best …

Normal‑tension glaucoma (NTG) is a multifactorial optic neuropathy which, similar to open‑
angle glaucomas, is characterized by progressive retinal ganglion cell death and …